SCHEMBL1259986

SCHEMBL1259986

O=C(O)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.42
ACLY P53396 2/20 0.37
TSHR P16473 2/20 0.34
KDM4E B2RXH2 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ODC1 P11926 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27299294 0.97 THRB (0.40) THRBACLYTSHRKDM4ETDP1
SCHEMBL1314472 0.83 THRB (0.50) THRBACLYTSHRKDM4ETDP1
SCHEMBL1132953 0.81 THRB (0.54) THRBACLYTSHRKDM4ETDP1
SCHEMBL5494043 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1
SCHEMBL5496340 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1
SCHEMBL5485668 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1
SCHEMBL5486150 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1
SCHEMBL5487374 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1
SCHEMBL981794 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1
SCHEMBL198881 0.79 THRB (0.58) THRBACLYTSHRKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559448-B2 Methods for functionalization hydrocarbons UNIVERSITY OF VIRGINA PATENT FOUNDATION (US) 2026-02-24 US claimed
WO-2025106778-A1 POLYMERS FOR THE REMOVAL OF PFAS FROM AQUEOUS COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME LUTUM TECHNOLOGY, LLC (US) 2025-05-22 WO claimed
WO-2025061960-A1 PROCESS FOR THE PURIFICATION OF PERFLUOROALKYL ACIDS CHIRON AS (NO) 2025-03-27 WO claimed
EP-4527829-A1 PROCESS FOR THE PURIFICATION OF PERFLUOROALKYL ACIDS Chiron AS (NO) 2025-03-26 EP claimed
US-20220185748-A1 METHODS FOR FUNCTIONALIZATION HYDROCARBONS UNIVERSITY OF VIRGINIA 2022-06-16 US claimed
WO-2020186195-A1 METHODS FOR FUNCTIONALIZATION HYDROCARBONS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2020-09-17 WO claimed
US-10450259-B2 Compositions and methods for hydrocarbon functionalization UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2019-10-22 US claimed
US-20170152207-A1 COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION UNITED STATES DEPARTMENT OF ENERGY 2017-06-01 US claimed
US-9604890-B2 Compositions and methods for hydrocarbon functionalization THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2017-03-28 US claimed
US-20160145188-A1 COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION UNITED STATES DEPARTMENT OF ENERGY 2016-05-26 US claimed
WO-2014210270-A1 COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2014-12-31 WO claimed
EP-0804735-A4 N-TERMINAL PROTEIN SEQUENCING REAGENTS AND METHODS WHICH FORM AMINO ACID DERIVATIVES HOPE CITY (US) 1999-12-22 EP claimed
US-5807748-A N-terminal protein sequencing reagents and methods which form amino acid detectable by a variety of techniques CITY OF HOPE (US) 1998-09-15 US claimed
EP-0804735-A1 N-TERMINAL PROTEIN SEQUENCING REAGENTS AND METHODS WHICH FORM AMINO ACID DERIVATIVES CITY OF HOPE (US) 1997-11-05 EP claimed
WO-1996002003-A1 N-TERMINAL PROTEIN SEQUENCING REAGENTS AND METHODS WHICH FORM AMINO ACID DERIVATIVES CITY OF HOPE (US) 1996-01-25 WO claimed
US-12628589-B2 Etching method using oxygen-containing hydrofluorocarbon L'Air Liquide, Societé´ Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) 2026-05-12 US disclosed
US-20260116798-A1 EFFECTIVE TREATMENT OF CHLOROTRIFLUOROETHYLENE (CTFE) OLIGOMERS AND DERIVATIVES UNIV CALIFORNIA (US) 2026-04-30 US disclosed
EP-0192742-A1 CYCLIC POLYPEPTIDES HAVING MU-RECEPTOR SPECIFICITY GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1986-09-03 EP disclosed
WO-1986001516-A1 CYCLIC POLYPEPTIDES HAVING MU-RECEPTOR SPECIFICITY GIBSON-STEPHENS NEUROPHARMACEUTICALS, INC. (US) 1986-03-13 WO disclosed
US-4160666-A Polymeric chemical sensitizers for organic photoconductive compositions EASTMAN KODAK COMPANY (US) 1979-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160145188-A1 COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION AHR, HMOX2, ALKBH3 THRB 2904/4885ACLY 2374/4885TSHR 3870/4885
US-20220185748-A1 METHODS FOR FUNCTIONALIZATION HYDROCARBONS AHR, AOX1, HMOX2 THRB 472/4885ACLY 1428/4885TSHR 442/4885
US-12559448-B2 Methods for functionalization hydrocarbons COXFA4, HAO2, PPARG THRB 20/4885ACLY 1166/4885TSHR 13/4885
US-10450259-B2 Compositions and methods for hydrocarbon functionalization AHR, HMOX2, HCCS THRB 3014/4885ACLY 2027/4885TSHR 3812/4885
US-20170152207-A1 COMPOSITIONS AND METHODS FOR HYDROCARBON FUNCTIONALIZATION AHR, HMOX2, ALKBH3 THRB 2904/4885ACLY 2374/4885TSHR 3870/4885
US-12628589-B2 Etching method using oxygen-containing hydrofluorocarbon HAO2, HYOU1, ZYX THRB 2681/4885ACLY 2600/4885TSHR 1454/4885
US-20260116798-A1 EFFECTIVE TREATMENT OF CHLOROTRIFLUOROETHYLENE (CTFE) OLIGOMERS AND DERIVATIVES ALDOA, PFKFB2, MGAM THRB 1335/4885ACLY 129/4885TSHR 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.