SCHEMBL12615

SCHEMBL12615

CC1CCC(CN2CCOCC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.53
THRB P10828 4/20 0.41
CHRM5 P08912 1/20 0.40
ADRA2C P18825 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35
JAK2 O60674 1/20 0.34
JAK1 P23458 1/20 0.34
TYK2 P29597 1/20 0.34
JAK3 P52333 1/20 0.34
USP2 O75604 1/20 0.34
SCN1A P35498 1/20 0.34
SCN4A P35499 1/20 0.34
SCN7A Q01118 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12716130 1.00 ACHE (0.53) ACHETHRBCHRM5ADRA2CALDH1A1
SCHEMBL14535216 0.89 CHRM5 (0.48) ACHETHRBCHRM5ADRA2CALDH1A1
SCHEMBL7562139 0.89 CHRM5 (0.48) ACHETHRBCHRM5ADRA2CALDH1A1
SCHEMBL15251336 0.88 ACHE (0.41) ACHETHRBCHRM5ADRA2CALDH1A1
SCHEMBL14375255 0.83 ACHE (0.64) ACHETHRBCHRM5ADRA2CHRH3
SCHEMBL21450694 0.83 THRB (0.41) ACHETHRBCHRM5ADRA2CALDH1A1
SCHEMBL26461975 0.82 ACHE (0.75) ACHETHRBCHRM5ADRA2CHRH3
SCHEMBL18727392 0.81 HRH3 (0.44) ACHETHRBALDH1A1GAAHRH3
SCHEMBL12716498 0.80 ACHE (0.65) ACHECHRM5ADRA2CHRH3SCN1A
SCHEMBL18999837 0.80 CHRM5 (0.56) ACHETHRBCHRM5ADRA2CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4209130-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF DSM Nutritional Products, LLC (US) 2023-07-12 EP disclosed
EP-4205553-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF DSM Nutritional Products, LLC (US) 2023-07-05 EP disclosed
EP-3250048-B1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF CADENA BIO INC (US) 2019-08-14 EP disclosed
EP-3459975-A1 POLYMERIC ACID CATALYSTS AND USES THEREOF Cadena Bio, Inc. (US) 2019-03-27 EP disclosed
WO-2018102687-A2 COMBINATION THERAPY FOR TREATING CANCER Epizyme, Inc. (US) 2018-06-07 WO disclosed
EP-2681247-B1 Polymers containing an acid group and their use as a catalyst CADENA BIO INC (US) 2018-04-04 EP disclosed
US-20160366909-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-12-22 US disclosed
EP-2499146-B1 TRICYCLIC PYRAZOL AMINE DERIVATIVES MERCK SERONO SA (CH) 2016-09-21 EP disclosed
WO-2016122887-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE ANIMAL FEED AND METHODS OF PRODUCING THEREOF MIDORI USA, INC. (US) 2016-08-04 WO disclosed
US-20160122447-A1 POLYMERIC ACID CATALYSTS AND USES THEREOF MIDORI USA, INC. (US) 2016-05-05 US disclosed
US-9205418-B2 Polymeric acid catalysts and uses thereof MIDORI USA, INC. (US) 2015-12-08 US disclosed
US-20150238948-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2015-08-27 US disclosed
US-20150202607-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2015-07-23 US disclosed
US-9079171-B2 Polymeric acid catalysts and uses thereof MIDORI USA, INC. (US) 2015-07-14 US disclosed
WO-2014159558-A1 POLYMERIC IONIC SALT CATALYSTS AND METHODS OF PRODUCING THEREOF Midori Renewables, Inc. (US) 2014-10-02 WO disclosed
US-20140060522-A1 METHODS OF PRODUCING SUGARS FROM BIOMASS FEEDSTOCKS HERCULES CAPITAL, INC. 2014-03-06 US disclosed
WO-2014031956-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS Midori Renewables, Inc. (US) 2014-02-27 WO disclosed
US-20130233308-A1 POLYMERIC ACID CATALYSTS AND USES THEREOF Midori Renewables, Inc. (US) 2013-09-12 US disclosed
WO-2011058149-A1 TRICYCLIC PYRAZOL AMINE DERIVATIVES MERCK SERONO S.A. (CH) 2011-05-19 WO disclosed
WO-2008152013-A1 INDOLINONE DERIVATIVES AND THEIR USE IN TREATING DISEASE-STATES SUCH AS CANCER BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238948-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING LIGNIN-CONTAINING MATERIALS USING SUCH CATALYSTS LCT, AGL, MGAM ACHE 1095/4885THRB 4609/4885CHRM5 4321/4885
US-20160366909-A1 OLIGOSACCHARIDE COMPOSITIONS FOR USE AS ANIMAL FEED AND METHODS OF PRODUCING THEREOF FUT5, FUT6, OSTC ACHE 3795/4885THRB 2421/4885CHRM5 3655/4885
US-20150202607-A1 POLYMERIC AND SOLID-SUPPORTED CATALYSTS, AND METHODS OF DIGESTING CELLULOSIC MATERIALS USING SUCH CATALYSTS MGAM, CEL, SI ACHE 504/4885THRB 4868/4885CHRM5 3686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.