SCHEMBL126457

SCHEMBL126457

c1cc(-c2ccc3oc4ccccc4c3c2)cc(-c2c3ccccc3c(-c3ccccc3-c3cccc4ccccc34)c3ccccc23)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.41
PLA2G4A P47712 3/20 0.41
PLA2G10 O15496 1/20 0.41
ALDH1A1 P00352 5/20 0.39
MAPT P10636 4/20 0.39
HPGD P15428 4/20 0.39
KDM4E B2RXH2 4/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
ALOX5 P09917 1/20 0.37
PIM1 P11309 2/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125879 0.96 ALDH1A1 (0.41) ALDH1A1MAPTHPGDKDM4EKMT2A
SCHEMBL126223 0.95 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL24090228 0.94 PIM1 (0.39) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL21163909 0.94 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL126463 0.93 ALDH1A1 (0.40) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL22854974 0.93 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL125731 0.92 ALOX5 (0.40) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL17945592 0.92 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL4079303 0.92 HCRTR1 (0.39) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT
SCHEMBL126279 0.92 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11665962-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-05-30 US disclosed
US-11665962-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-05-30 US disclosed
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2022-01-27 US disclosed
US-20210384445-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-12-09 US disclosed
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2021-06-01 US disclosed
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2020-08-13 US disclosed
US-10566541-B2 Aromatic amine derivative, material for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2020-02-18 US disclosed
US-10388885-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2019-08-20 US disclosed
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-23 US disclosed
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 US disclosed
US-8512875-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-08-20 US disclosed
US-8512875-B2 Anthracene derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2013-08-20 US disclosed
US-20130153878-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-06-20 US disclosed
US-20130153878-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-06-20 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120056165-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-03-08 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-02-23 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. 2011-12-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220029097-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 PLA2G2A 4023/4885PLA2G4A 3929/4885PLA2G10 4070/4885
US-20120043533-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AOC2, AOC3, H1-4 PLA2G2A 3455/4885PLA2G4A 3579/4885PLA2G10 3775/4885
US-20200259087-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING THE SAME AR, H1-4, AFF4 PLA2G2A 4023/4885PLA2G4A 3929/4885PLA2G10 4070/4885
US-20210384445-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE ESR1, EML4, L1CAM PLA2G2A 4198/4885PLA2G4A 4635/4885PLA2G10 4340/4885
US-10263191-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 PLA2G2A 4023/4885PLA2G4A 3929/4885PLA2G10 4070/4885
US-20110297923-A1 Aromatic amine derivative and organic electroluminescent element using same H1-4, H1-2, H1-0 PLA2G2A 3874/4885PLA2G4A 4262/4885PLA2G10 4085/4885
US-10270040-B2 Oxygen-containing fused ring amine compound, sulfur-containing fused ring amine compound and organic electroluminescence device AOC2, SQOR, AOC1 PLA2G2A 4152/4885PLA2G4A 4692/4885PLA2G10 4509/4885
US-11024806-B2 Aromatic amine derivative, and organic electroluminescent element comprising the same AR, H1-4, AFF4 PLA2G2A 4023/4885PLA2G4A 3929/4885PLA2G10 4070/4885
US-11665962-B2 Organic electroluminescence element and electronic device ESR1, EML4, L1CAM PLA2G2A 4198/4885PLA2G4A 4635/4885PLA2G10 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.