Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1109066 | 0.87 | CYP2A6 (0.48) | ALDH1A1KDM4ECYP2A6ALDH1A3HSD17B10 | |
| SCHEMBL8808020 | 0.84 | ADRA2A (0.48) | PARP10ALDH1A1SMN1; SMN2FURINKMT2A | |
| SCHEMBL5050902 | 0.84 | PARP10 (0.65) | PARP10PARP3ALDH1A1KDM4ELMNA | |
| SCHEMBL1663469 | 0.84 | PARP10 (0.65) | PARP10PARP3ALDH1A1KDM4ELMNA | |
| SCHEMBL24628725 | 0.80 | DRD1 (0.44) | ALDH1A1KDM4ECYP2A6ALDH1A3DRD1 | |
| SCHEMBL12182786 | 0.78 | RAB9A (0.56) | ALDH1A1KDM4ELMNASMN1; SMN2KMT2A | |
| Fluoromethane SCHEMBL28219755 | 0.78 | ALDH1A1 (0.62) | PARP10PARP3ALDH1A1KDM4ELMNA | |
| SCHEMBL10620953 | 0.76 | LTA4H (0.57) | PARP10ALDH1A1HSD17B10 | |
| SCHEMBL888020 | 0.76 | ALDH1A1 (0.59) | PARP10PARP3ALDH1A1KDM4ELMNA | |
| SCHEMBL97639 | 0.76 | ALDH1A1 (0.59) | PARP10PARP3ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288528-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |
| US-20110112464-A1 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2011-05-12 | — | — | US | disclosed |