Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390048 | 0.83 | CASP6 (0.44) | METAP1LMNAGAATSPOPKM | |
| SCHEMBL9918982 | 0.77 | SRD5A1 (0.50) | METAP1GAAPKMSRD5A1SRD5A2 | |
| SCHEMBL1925736 | 0.76 | OPRK1 (0.55) | LMNAGAATSPOPKMSRD5A1 | |
| SCHEMBL12706548 | 0.76 | RNASEH1 (0.49) | GAAPKMSRD5A1CASP6MEN1 | |
| SCHEMBL1925311 | 0.73 | PKM (0.59) | LMNAGAATSPOPKMSRD5A1 | |
| SCHEMBL23957375 | 0.68 | P2RX7 (0.42) | METAP1LMNAGAASRD5A1SRD5A2 | |
| SCHEMBL4307204 | 0.68 | CYP11B2 (0.44) | METAP1LMNASRD5A1SRD5A2OPRK1 | |
| SCHEMBL29481934 | 0.68 | P2RX7 (0.42) | METAP1LMNAGAASRD5A1SRD5A2 | |
| SCHEMBL29581704 | 0.68 | METAP1 (0.47) | METAP1F7PARP1F3PARP10 | |
| SCHEMBL4896509 | 0.68 | METAP1 (0.47) | METAP1F7PARP1F3PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314593-A1 | Platelet ADP receptor inhibitors | Portola Pharmaceuticals, Inc. (US) | 2011-04-27 | — | — | EP | disclosed |