Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 10/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028313 | 0.85 | ILK (0.49) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL25028187 | 0.79 | MMP2 (0.46) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL10025480 | 0.74 | RAB9A (1.00) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11497248 | 0.74 | MMP2 (0.55) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL16689142 | 0.73 | NPC1 (0.70) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL27490376 | 0.73 | MMP2 (0.40) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7811413 | 0.72 | IDO1 (0.50) | RAB9ANPC1MMP2MMP9MMP8 | |
| SCHEMBL31712298 | 0.72 | RAB9A (0.58) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL3053833 | 0.72 | APP (0.60) | RAB9AKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL1992041 | 0.72 | APP (1.00) | RAB9AKDM4EALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617249-B2 | Benzoheterocyclic anti-bacterial agents | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617249-B2 | Benzoheterocyclic anti-bacterial agents | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2017-04-11 | — | — | US | disclosed |
| US-20130143841-A1 | BENZOHETEROCYCLIC ANTI-BACTERIAL AGENTS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130143841-A1 | BENZOHETEROCYCLIC ANTI-BACTERIAL AGENTS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-06-06 | — | — | US | disclosed |
| US-8362268-B2 | Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362268-B2 | Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110086817-A1 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009158118-A2 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086817-A1 | ANTI-BACTERIAL AGENTS FROM BENZO[D]HETEROCYCLIC SCAFFOLDS FOR PREVENTION AND TREATMENT OF MULTIDRUG RESISTANT BACTERIA | SBDS, PYCARD, AAAS | RAB9A 2088/4885KDM4E 780/4885ALDH1A1 2252/4885 |
| US-20130143841-A1 | BENZOHETEROCYCLIC ANTI-BACTERIAL AGENTS | MRPL21, BCOR, BCR | RAB9A 2505/4885KDM4E 749/4885ALDH1A1 1985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.