Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086414 | 0.91 | LMNA (0.68) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL29429254 | 0.89 | ALDH1A1 (0.53) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11344335 | 0.89 | ALDH1A1 (0.53) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL30395472 | 0.89 | ALDH1A1 (0.53) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL18309270 | 0.88 | L3MBTL1 (0.60) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL7771564 | 0.84 | LMNA (0.49) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10419263 | 0.84 | KDM4E (0.57) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL2903384 | 0.82 | L3MBTL1 (0.55) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL18309273 | 0.82 | L3MBTL1 (0.55) | LMNAALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL22564796 | 0.82 | LMNA (0.48) | LMNAALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297374-A1 | In Situ Moisture Generation and Use of Polyfunctional Alcohols for Crosslinking of Silane-Functionalized Resins | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-11-25 | — | — | US | claimed |
| EP-2207851-A2 | IN SITU MOISTURE GENERATION AND USE OF POLYFUNCTIONAL ALCOHOLS FOR CROSSLINKING OF SILANE-FUNCTIONALIZED RESINS | Dow Global Technologies Inc. (US) | 2010-07-21 | — | — | EP | claimed |
| WO-2009058545-A2 | IN SITU MOISTURE GENERATION AND USE OF POLYFUNCTIONAL ALCOHOLS FOR CROSSLINKING OF SILANE-FUNCTIONALIZED RESINS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-05-07 | — | — | WO | claimed |
| US-6409949-B1 | FEED RESIN CONTAINING CHAIN EXTENSION AGENT IS SUBJECTED TO MIXING WHILE BEING DEAERATED UNDER REDUCED PRESSURE IN SINGLE THICKENING CHAMBER | KABUSHIKI KAISHA KOBE SEIKO SHO (KOBE STEEL, LTD.) (JP) | 2002-06-25 | — | — | US | claimed |
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| US-4104297-A | Thermoplastic polyesters prepared from dicarboxylic acids containing N-heterocyclic rings | CIBA-GEIGY CORPORATION (US) | 1978-08-01 | — | — | US | claimed |
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-11566015-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| CN-114829443-A | Polysiloxane functionalized polyurethanes for enhancing the hydrophobicity of surfaces | 科思创知识产权两合公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-109642009-B | Silane-functional polymeric polyurethanes | 科思创德国股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| US-20210238164-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2021-08-05 | — | — | US | disclosed |
| WO-2021094229-A1 | POLYSILOXANE-FUNCTIONALIZED POLYURETHANES FOR BOOSTING THE HYDROPHOBICITY OF SURFACES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-05-20 | — | — | WO | disclosed |
| US-10941158-B2 | Pyrazole ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2021-03-09 | — | — | US | disclosed |
| US-4456723-A | POLYESTER WITH ANHYDROUS CALCIUM PHOSPHATE | CIBA-GEIGY CORPORATION (US) | 1984-06-26 | — | — | US | disclosed |
| US-4401784-A | ADDING DOLOMITE TO INCREASE STIFFNESS AND DIMENSIONAL STABILITY UNDER HEAT | CIBA-GEIGY CORPORATION (US) | 1983-08-30 | — | — | US | disclosed |
| US-4289896-A | PHOSPHONIC ACID CATALYST | CIBA-GEIGY CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4255152-A | USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING | CIBA-GEIGY CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4148956-A | TOUGH POLYESTERS WITH ACRYLONITRILE-STYRENE, MODIFIED WITH ACRYLATE, COPOLYMER | ALKOR GMBH (DE) | 1979-04-10 | — | — | US | disclosed |
| US-4108834-A | N,N-HETEROCYCLIC DIOLS | CIBA-GEIGY CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |
| US-4104297-A | Thermoplastic polyesters prepared from dicarboxylic acids containing N-heterocyclic rings | CIBA-GEIGY CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566015-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | LMNA 4172/4885ALDH1A1 2977/4885KMT2A 1341/4885 |
| US-20210238164-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | MC3R, MC1R, MC2R | LMNA 4172/4885ALDH1A1 2977/4885KMT2A 1341/4885 |
| US-10941158-B2 | Pyrazole ACC inhibitors and uses thereof | ACACA, ACACB, PC | LMNA 3921/4885ALDH1A1 185/4885KMT2A 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.