Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.75 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.75 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.75 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.75 |
| ▸ | LDHA | P00338 | 1/20 | 0.75 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.75 |
| ▸ | FBP1 | P09467 | 1/20 | 0.75 |
| ▸ | SRC | P12931 | 1/20 | 0.75 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.75 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.75 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.75 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.75 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.75 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.75 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23647917 | 1.00 | ADORA1 (0.75) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL9990451 | 1.00 | ADORA1 (0.75) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL29388941 | 1.00 | ADORA1 (0.75) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL20942825 | 1.00 | ADORA1 (0.75) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL29496215 | 0.96 | P2RY1 (0.80) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| Adenosine Phosphate SCHEMBL3828789 | 0.90 | P2RY1 (0.92) | ADORA1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL3694223 | 0.90 | ADORA3 (0.76) | ADORA1SMN1; SMN2 | |
| SCHEMBL25413594 | 0.90 | ADORA3 (0.76) | ADORA1SMN1; SMN2 | |
| SCHEMBL29796608 | 0.90 | ADORA3 (0.76) | ADORA1SMN1; SMN2 | |
| SCHEMBL3694227 | 0.90 | ADORA3 (0.76) | ADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249473-B2 | Compositions and methods for the identification of inhibitors of retroviral infection | Trana Discover, Inc. (US) | 2016-02-02 | — | — | US | claimed |
| US-20140121124-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION | GUENTHER RICHARD H (US) | 2014-05-01 | — | — | US | claimed |
| EP-2201118-B1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION | TRANA DISCOVERY (US) | 2012-04-18 | — | — | EP | claimed |
| US-20100291032-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION | TRANA DISCOVERY (US) | 2010-11-18 | — | — | US | claimed |
| EP-2201118-A2 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION | Trana Discovery (US) | 2010-06-30 | — | — | EP | claimed |
| WO-2009036299-A2 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION | TRANA DISCOVERY (US) | 2009-03-19 | — | — | WO | claimed |
| WO-2024148237-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC INHIBITORS OF MYCOBACTERIA, INCLUDING M. TUBERCULOSIS | TRANA DISCOVERY, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | TRANA DISCOVERY, INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20190024152-A1 | IDENTIFICATION OF SELECTED SPECTRUM ANTIBIOTICS | TRANA DISCOVERY, INC. (US) | 2019-01-24 | — | — | US | disclosed |
| US-20190022100-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY INC (US) | 2019-01-24 | — | — | US | disclosed |
| US-10098887-B2 | Antiviral compounds and methods of use thereof | TRANA DISCOVERY, INC. (US) | 2018-10-16 | — | — | US | disclosed |
| US-9877956-B2 | Antiviral compounds and methods of use thereof | TRANA DISCOVERY, INC. (US) | 2018-01-30 | — | — | US | disclosed |
| US-9677143-B2 | Compositions and methods for the identification of inhibitors of retroviral infection | TRANA DISCOVERY, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20080199870-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY, INC. | 2008-08-21 | — | — | US | disclosed |
| EP-1944321-A2 | Methods and compositions for determining the purity of chemically synthesized nucleic acids | North Carolina State University (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2008064304-A9 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY INC (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008064304-A2 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| US-6962785-B2 | Antibacterial and antiviral agents and methods of screening for the same | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-11-08 | — | — | US | disclosed |
| US-6929907-B2 | Used for detecting incomplete deprotection of a synthetic oligonucleotide by immunoassay | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-08-16 | — | — | US | disclosed |
| US-6461815-B1 | DETERMINATION IF DRUG INHIBITS BINDING OF TDNA TO RIBOSOME | NORTH CAROLINA STATE UNIVERSITY | 2002-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316371-B2 | Screening methods for identifying specific Staphylococcus aureus inhibitors | NSUN3, RNGTT, TRMT1 | ADORA1 2579/4885DNPH1 3432/4885PRKAB2 3018/4885 |
| US-10098887-B2 | Antiviral compounds and methods of use thereof | TYMP, MAVS, ZC3HAV1 | ADORA1 2791/4885DNPH1 3165/4885PRKAB2 4480/4885 |
| US-20100291032-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION | TRMT1L, TRMT1, TARBP1 | ADORA1 2198/4885DNPH1 4171/4885PRKAB2 4120/4885 |
| US-20080199870-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | NSUN3, RNGTT, TARBP1 | ADORA1 4078/4885DNPH1 2127/4885PRKAB2 1666/4885 |
| US-20190022100-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TYMP, MAVS, ZC3HAV1 | ADORA1 2791/4885DNPH1 3165/4885PRKAB2 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.