SCHEMBL29388941

SCHEMBL29388941

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1OC1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.75
DNPH1 O43598 1/20 0.75
PRKAB2 O43741 1/20 0.75
TRPM2 O94759 1/20 0.75
LDHA P00338 1/20 0.75
ADRB2 P07550 1/20 0.75
FBP1 P09467 1/20 0.75
SRC P12931 1/20 0.75
P2RY2 P41231 1/20 0.75
P2RY1 P47900 1/20 0.75
PRKAG1 P54619 1/20 0.75
PRKAA2 P54646 1/20 0.75
PDE4D Q08499 1/20 0.75
KCNH2 Q12809 1/20 0.75
PRKAA1 Q13131 1/20 0.75
PDE3A Q14432 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
TAS1R3 Q7RTX0 1/20 0.75
TAS1R1 Q7RTX1 1/20 0.75
P2RY11 Q96G91 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275138 1.00 ADORA1 (0.75) ADORA1DNPH1PRKAB2TRPM2LDHA
SCHEMBL23647917 1.00 ADORA1 (0.75) ADORA1DNPH1PRKAB2TRPM2LDHA
SCHEMBL9990451 1.00 ADORA1 (0.75) ADORA1DNPH1PRKAB2TRPM2LDHA
SCHEMBL20942825 1.00 ADORA1 (0.75) ADORA1DNPH1PRKAB2TRPM2LDHA
SCHEMBL29496215 0.96 P2RY1 (0.80) ADORA1DNPH1PRKAB2TRPM2LDHA
Adenosine Phosphate SCHEMBL3828789 0.90 P2RY1 (0.92) ADORA1DNPH1PRKAB2TRPM2LDHA
SCHEMBL3694223 0.90 ADORA3 (0.76) ADORA1SMN1; SMN2
SCHEMBL25413594 0.90 ADORA3 (0.76) ADORA1SMN1; SMN2
SCHEMBL29796608 0.90 ADORA3 (0.76) ADORA1SMN1; SMN2
SCHEMBL3694227 0.90 ADORA3 (0.76) ADORA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
US-20250019719-A1 Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2025-01-16 US claimed
US-20240279676-A1 CONSTRUCTS AND METHODS FOR PREPARING CIRCULAR RNAS AND USE THEREOF Shanghai Circode Biomed Co., Ltd. (CN) 2024-08-22 US claimed
EP-4347841-A1 CONSTRUCTS AND METHODS FOR PREPARING CIRCULAR RNAS AND USE THEREOF Shanghai Circode Biomed Co., Ltd. (CN) 2024-04-10 EP claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
CN-115943307-A MR1 ligands and pharmaceutical compositions for immunomodulation 巴塞尔大学 2023-04-07 CN claimed
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION UNIVERSITÄT BASEL (CH) 2023-03-30 US claimed
WO-2022247943-A1 CONSTRUCTS AND METHODS FOR PREPARING CIRCULAR RNAS AND USE THEREOF Shanghai Circode Biomed Co., Ltd. (CN) 2022-12-01 WO claimed
EP-4090969-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION Universität Basel (CH) 2022-11-23 EP claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS MODERNATX, INC. (US) 2026-05-28 US disclosed
CN-113396219-B Purification of mRNA by tangential flow filtration ETHRIS GMBH (DE) 2026-05-26 CN disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
WO-2026107055-A1 HEPATITIS B VIRUS VACCINE AND METHODS OF USE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-05-21 WO disclosed
US-20260137630-A1 COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS AND ACTIVATION OF T CELLS THE TRUSTEES OF THE UNIV OF PENNSYLVANIA (US) 2026-05-21 US disclosed
CN-107949424-B TAT-induced CRISPR/endonuclease-based gene editing 天普大学-联邦高等教育系统 2022-03-01 CN disclosed
US-20220054525-A1 DELIVERY OF RNA TO TRIGGER MULTIPLE IMMUNE PATHWAYS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-02-24 US disclosed
WO-2022032154-A2 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2022-02-10 WO disclosed
US-20220031631-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF MODERNATX, INC. (US) 2022-02-03 US disclosed
EP-3394093-B1 METHODS OF USING OX40 LIGAND ENCODING POLYNUCLEOTIDES MODERNATX INC (US) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260137630-A1 COMPOSITIONS AND METHODS FOR T CELL TARGETED DELIVERY OF THERAPEUTIC AGENTS AND ACTIVATION OF T CELLS LCP2, CD47, CD4 ADORA1 3112/4885DNPH1 3747/4885PRKAB2 3836/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT ADORA1 4370/4885DNPH1 4665/4885PRKAB2 1696/4885
US-20220031631-A1 HIGH-PURITY PEG LIPIDS AND USES THEREOF LIPA, HDLBP, PLTP ADORA1 4639/4885DNPH1 2573/4885PRKAB2 3423/4885
US-20230099822-A1 MR1 LIGANDS AND PHARMACEUTICAL COMPOSITIONS FOR IMMUNOMODULATION MRGPRX1, MRGPRX2, CD47 ADORA1 16/4885DNPH1 3133/4885PRKAB2 1632/4885
US-20260146262-A1 METHODS OF LIPID NANOPARTICLE PRODUCTION IN CROSS-MIXERS ELAVL1, IGF2BP2, FUS ADORA1 2437/4885DNPH1 4723/4885PRKAB2 1734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.