Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | CA7 | P43166 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eschweilenol C SCHEMBL1699342 | 0.88 | KDM4E (0.54) | MAPTKDM4ECA12RECQLTDP1 | |
| Eschweilenol C SCHEMBL15359344 | 0.88 | KDM4E (0.54) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL1444961 | 0.85 | SOST (0.60) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL1279584 | 0.85 | SOST (0.60) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL1279902 | 0.84 | SOST (0.59) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL1279510 | 0.81 | MAPT (0.54) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL31237905 | 0.76 | CA12 (0.52) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL30658623 | 0.76 | RELA (0.60) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL2355138 | 0.76 | KDM4E (0.88) | MAPTKDM4ECA12RECQLTDP1 | |
| SCHEMBL2369012 | 0.75 | KDM4E (0.77) | MAPTKDM4ECA12RECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9351492-B2 | Anti-biofilm compositions and methods for using | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-05-31 | — | — | US | claimed |
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2014-09-18 | — | — | US | claimed |
| US-8741855-B2 | Anti-biofilm compositions and methods for using | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-03 | — | — | US | claimed |
| EP-2624702-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | The Board of Trustees of The University of Arkansas (US) | 2013-08-14 | — | — | EP | claimed |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | US | claimed |
| WO-2012048119-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2012-04-12 | — | — | WO | claimed |
| US-9351492-B2 | Anti-biofilm compositions and methods for using | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2624702-B1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | UNIV ARKANSAS (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-1734949-B1 | PURIFICATIONS OF ELLAGITANNINS | UNIV CALIFORNIA (US) | 2015-05-20 | — | — | EP | disclosed |
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | BOARD OF TRUSTEES UNIVERSITY OF ARKANSAS (US) | 2014-09-18 | — | — | US | disclosed |
| US-8741855-B2 | Anti-biofilm compositions and methods for using | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2014-06-03 | — | — | US | disclosed |
| EP-2624702-A2 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | The Board of Trustees of The University of Arkansas (US) | 2013-08-14 | — | — | EP | disclosed |
| EP-2481298-A2 | USE OF PLANT EXTRACTS AS PREBIOTICS, COMPOSTIONS AND FOODS CONTAINING SUCH EXTRACTS | Probelte Pharma, S.A. (ES) | 2012-08-01 | — | — | EP | disclosed |
| US-7638640-B2 | total pomegranate tannins (TPT) including punicalagin; nutraceutical for cardiovascular health | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-12-29 | — | — | US | disclosed |
| EP-1734949-A4 | PURIFICATIONS OF ELLAGITANNINS | UNIV CALIFORNIA (US) | 2009-07-22 | — | — | EP | disclosed |
| US-20080318877-A1 | punicalagin extraction; commercial scale; nutraceutical for cardiovascular health | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-25 | — | — | US | disclosed |
| EP-1967079-A2 | Process and apparatus for preparing pomegranate extracts | Probelte Pharma, S.A. (ES) | 2008-09-10 | — | — | EP | disclosed |
| EP-1734949-A1 | PURIFICATIONS OF ELLAGITANNINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20060211635-A1 | total pomegranate tannins (TPT) including punicalagin; nutraceutical for cardiovascular health | THE REGENTS OF THE UNIVERSITY OF CLIFORNIA | 2006-09-21 | — | — | US | disclosed |
| WO-2005097106-A1 | PURIFICATIONS OF ELLAGITANNINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140271777-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | TIMP3, MMP13, MMP8 | MAPT 3634/4885KDM4E 1528/4885CA12 2383/4885 |
| US-20120088671-A1 | ANTI-BIOFILM COMPOSITIONS AND METHODS FOR USING | TIMP3, MMP13, MMP8 | MAPT 3634/4885KDM4E 1528/4885CA12 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.