Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSH | P09668 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632987 | 0.82 | REN (0.48) | RENCNR2BIRC2CTSKCTSL | |
| SCHEMBL13744623 | 0.80 | MME (0.54) | MME | |
| SCHEMBL13825642 | 0.79 | ALDH1A1 (0.52) | CNR2CTSLCTSBMME | |
| SCHEMBL4237428 | 0.77 | MMEL1 (0.48) | MME | |
| SCHEMBL13825640 | 0.76 | MME (0.50) | MME | |
| SCHEMBL14392786 | 0.76 | CTRB1 (0.53) | RENCTSK | |
| SCHEMBL14611003 | 0.76 | CTRB1 (0.53) | RENCTSK | |
| SCHEMBL12228016 | 0.74 | CYP3A4 (0.47) | — | |
| SCHEMBL27846893 | 0.74 | EPHX1 (0.53) | — | |
| SCHEMBL6343323 | 0.74 | EPHX1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289887-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |