Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 4/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSH | P09668 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14265119 | 0.82 | REN (0.41) | RENBIRC2CTSKCTSLCTSB | |
| SCHEMBL12829169 | 0.82 | REN (0.52) | RENBIRC2CTSKCTSLCTSB | |
| SCHEMBL1486271 | 0.82 | IL1RN (0.61) | ANPEPIL1RNERAP2BIRC2 | |
| SCHEMBL12228016 | 0.77 | CYP3A4 (0.47) | CYP3A4MAPK1 | |
| SCHEMBL5812534 | 0.75 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL5812528 | 0.75 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL21570275 | 0.75 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL21570273 | 0.75 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPCSNK1E | |
| SCHEMBL14611003 | 0.74 | CTRB1 (0.53) | RENCTSKCYP3A4MAPK1 | |
| SCHEMBL14392786 | 0.74 | CTRB1 (0.53) | RENCTSKCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| US-7326799-B2 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2008-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | REN, CMA1, AKR1A1 | REN 1/4885LAP3 1340/4885ANPEP 31/4885 |
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | AKR1C1, AKR1C4, AADAC | REN 786/4885LAP3 3767/4885ANPEP 379/4885 |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | CMA1, REN, TPSAB1 | REN 2/4885LAP3 934/4885ANPEP 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.