Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071528 | 0.93 | DPP4 (0.36) | ACELMNASMN1; SMN2P2RY12F2 | |
| SCHEMBL13072076 | 0.91 | ACE (0.35) | ACELMNASMN1; SMN2P2RY12F2 | |
| SCHEMBL13071527 | 0.91 | DPP4 (0.39) | ACELMNASMN1; SMN2P2RY12F2 | |
| SCHEMBL13071404 | 0.90 | ALDH1A1 (0.39) | ACELMNASMN1; SMN2 | |
| SCHEMBL13071526 | 0.86 | UBE2M (0.35) | ACEF2F10 | |
| SCHEMBL13071880 | 0.85 | UBE2M (0.34) | ACESMN1; SMN2 | |
| SCHEMBL13071425 | 0.85 | ACE (0.38) | ACEF2 | |
| SCHEMBL13071897 | 0.85 | F2 (0.41) | ACEF2F10 | |
| SCHEMBL13071388 | 0.84 | HTR1A (0.38) | ACELMNASMN1; SMN2F2F10 | |
| SCHEMBL12831720 | 0.84 | ACE (0.37) | ACEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038293-A1 | CYCLIC PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-03-31 | — | — | WO | disclosed |