Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 4/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 2/20 | 0.32 |
| ▸ | F2R | P25116 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | TRHR | P34981 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071404 | 0.91 | ALDH1A1 (0.39) | UBE2MDCUN1D1DPP4XIAPALDH1A1 | |
| SCHEMBL13071527 | 0.90 | DPP4 (0.39) | DPP4XIAPALDH1A1ACESMN1; SMN2 | |
| SCHEMBL13071921 | 0.90 | DPP4 (0.35) | UBE2MDCUN1D1DPP4XIAPF2R | |
| SCHEMBL13072076 | 0.89 | ACE (0.35) | F2RALDH1A1ACESMN1; SMN2TACR1 | |
| SCHEMBL13071528 | 0.88 | DPP4 (0.36) | DPP4F2RACESMN1; SMN2 | |
| SCHEMBL13071526 | 0.87 | UBE2M (0.35) | UBE2MDCUN1D1XIAPF2RACE | |
| SCHEMBL13071393 | 0.87 | DPP4 (0.32) | UBE2MDCUN1D1DPP4XIAPF2R | |
| SCHEMBL13071408 | 0.86 | XIAP (0.33) | UBE2MDCUN1D1DPP4XIAPF2R | |
| SCHEMBL12831754 | 0.85 | ACE (0.41) | ACESMN1; SMN2 | |
| SCHEMBL13071891 | 0.80 | XIAP (0.33) | UBE2MDCUN1D1XIAPS1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142842-A9 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2009142842-A2 | NOVEL MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2009-11-26 | — | — | WO | disclosed |