Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13362096 | 0.85 | HTR1A (0.51) | ALDH1A1CCR1 | |
| SCHEMBL11294977 | 0.85 | CCR1 (0.46) | ALDH1A1CCR1 | |
| SCHEMBL2205957 | 0.85 | CASP6 (0.59) | — | |
| SCHEMBL4174848 | 0.84 | L3MBTL1 (0.61) | ALDH1A1CCR1 | |
| SCHEMBL15358736 | 0.83 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL4170621 | 0.82 | MAPT (0.47) | ALDH1A1CCR1 | |
| SCHEMBL2723108 | 0.82 | ALK (0.53) | ALDH1A1CCR1 | |
| SCHEMBL4171024 | 0.82 | CCR1 (0.51) | ALDH1A1CCR1 | |
| SCHEMBL13178104 | 0.82 | SIRT6 (0.52) | CCR1 | |
| SCHEMBL4172479 | 0.82 | ALK (0.50) | ALDH1A1CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478539-B | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-114478539-A | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-05-13 | — | — | CN | disclosed |
| WO-2011034907-A2 | PROTEIN KINASE CONJUGATES AND INHIBITORS | AVILA THERAPEUTICS, INC. (US) | 2011-03-24 | — | — | WO | disclosed |