Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | FOS | P01100 | 1/20 | 0.55 |
| ▸ | JUN | P05412 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.49 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284284 | 1.00 | RAB9A (0.60) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL4821062 | 0.92 | KMT2A (0.68) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL3136872 | 0.92 | KMT2A (0.68) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL21235162 | 0.84 | TYR (0.61) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL23866749 | 0.82 | LMNA (0.58) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL5856758 | 0.82 | CYP1B1 (0.57) | RAB9AKMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL8878144 | 0.82 | HSD11B1 (0.62) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL4731715 | 0.82 | CYP1A2 (0.62) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL6851216 | 0.82 | HSD11B1 (0.62) | RAB9AKMT2ANPC1ALDH1A1MEN1 | |
| SCHEMBL4731717 | 0.82 | CYP1A2 (0.62) | RAB9AKMT2ANPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1100155-A | — | — | None | — | — | JP | disclosed |
| EP-2443099-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120088664-A1 | Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2010146113-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES HAVING A 5- SULFUR SUBSTITUENT | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
| JP-H01100155-A | CINNAMOYLALKANE DERIVATIVE COMPOUND | NIPPON OIL & FATS CO LTD | 1989-04-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088664-A1 | Antifungal 1,2,4-triazolyl derivatives having a 5-sulfur subtituent | STS, TST, ERG28 | RAB9A 2809/4885KMT2A 2938/4885NPC1 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.