Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136872 | 1.00 | KMT2A (0.68) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL1284284 | 0.92 | RAB9A (0.60) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL21235162 | 0.92 | TYR (0.61) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL1284286 | 0.92 | RAB9A (0.60) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL23866749 | 0.90 | LMNA (0.58) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL6851216 | 0.90 | HSD11B1 (0.62) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL4731717 | 0.90 | CYP1A2 (0.62) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL8878144 | 0.90 | HSD11B1 (0.62) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL4731715 | 0.90 | CYP1A2 (0.62) | KMT2ANPC1MEN1ALDH1A1LMNA | |
| SCHEMBL6047363 | 0.89 | NPC1 (0.72) | KMT2ANPC1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | claimed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| JP-4134041-A | — | — | None | — | — | JP | disclosed |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2021-11-11 | — | — | US | disclosed |
| EP-3185843-B1 | GEL COMPOSITION AND GEL COMPRISING A UV FILTER | OREAL (FR) | 2021-08-11 | — | — | EP | disclosed |
| EP-2872107-B1 | COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| EP-2872107-B1 | COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | L'OREAL (FR) | 2020-11-19 | — | — | US | disclosed |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2020-01-30 | — | — | US | disclosed |
| EP-2945602-B1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND AN INSOLUBLE ORGANIC UV-SCREENING AGENT AND/OR AN INSOLUBLE INORGANIC UV- SCREENING AGENT | L'ORÉAL (FR) | 2018-01-10 | — | — | EP | disclosed |
| US-20050058612-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UV radiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | L'OREAL (FR) | 2005-03-17 | — | — | US | disclosed |
| US-6818206-B2 | CONTROLLING PARTICLE SIZES; TOPICAL APPLYING | L'OREAL (FR) | 2004-11-16 | — | — | US | disclosed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | disclosed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | disclosed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| US-20030129151-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | L'OREAL (FR) | 2003-07-10 | — | — | US | disclosed |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | L'OREAL (FR) | 2003-03-20 | — | — | US | disclosed |
| JP-H04134041-A | P-XYLIDENE KETONE DERIVATIVE, ULTRAVIOLET ABSORBER CONTAINING SAID DERIVATIVE AND COSMETIC CONTAINING SAID ABSORBER | KAO CORP | 1992-05-07 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030129151-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UVradiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | CUTA, HNRNPU, ERCC5 | KMT2A 4704/4885NPC1 561/4885MEN1 3351/4885 |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | PCNA, ERCC1, XRCC6 | KMT2A 3095/4885NPC1 1496/4885MEN1 672/4885 |
| US-20050058612-A1 | Use of amphiphilic copolymers to stabilize dispersions of insoluble organic compounds for screening out UV radiation, dispersions stabilized with these copolymers and cosmetic compositions containing them | CUTA, ERCC5, ERCC1 | KMT2A 4523/4885NPC1 379/4885MEN1 3234/4885 |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SUCLG1, CUTA, DLD | KMT2A 3376/4885NPC1 2529/4885MEN1 4027/4885 |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | PRKDC, AHR, TYR | KMT2A 1006/4885NPC1 2650/4885MEN1 4562/4885 |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | KMT2A 3476/4885NPC1 3005/4885MEN1 2561/4885 |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | KMT2A 3476/4885NPC1 3005/4885MEN1 2561/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | KMT2A 3626/4885NPC1 3007/4885MEN1 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.