SCHEMBL1284375

SCHEMBL1284375

C=C(CC(=O)OC=O)C(=O)OC=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10026903 0.81 ALOX15 (0.46)
SCHEMBL156823 0.79 ALOX15 (0.31)
SCHEMBL151814 0.79 MGAM (0.36) TSHR
Ethylene SCHEMBL28352553 0.77 ALOX15 (0.30)
SCHEMBL619372 0.76
SCHEMBL22643409 0.74 LMNA (0.41) TSHR
SCHEMBL1436576 0.73 TSHR (0.40) TSHR
SCHEMBL19746162 0.73
SCHEMBL19746156 0.73
SCHEMBL4021010 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4744795-A Terpolymers of ethyl acrylate/methacrylic acid/unsaturated acid ester of alcohols and acids as anti-settling agents in coal water slurries DIAMOND SHAMROCK CHEMICALS COMPANY (US) 1988-05-17 US claimed
US-4663385-A Process for thickening with copolymers of alkyl poly (oxyalkylene) itaconic di-esters ROHM AND HAAS (US) 1987-05-05 US claimed
EP-0109820-B1 COPOLYMERS OF ALKYL POLY(OXYALKYLENE) ITACONATES AND THICKENING PROCESSES USING THEM ROHM AND HAAS COMPANY (US) 1987-04-29 EP claimed
EP-0109820-A1 Copolymers of alkyl poly(oxyalkylene) itaconates and thickening processes using them ROHM AND HAAS COMPANY (US) 1984-05-30 EP claimed
CN-115746277-B Bio-based flame-retardant unsaturated polyester for wood enhancement modification and preparation and application thereof 华南农业大学 2024-03-12 CN disclosed
US-20230312615-A1 METAL-ORGANIC FRAMEWORKS FOR THE STORAGE AND DELIVERY OF HYDROGEN SULFIDE, METHODS OF MAKING AND USES OF SAME CORNELL UNIVERSITY 2023-10-05 US disclosed
US-20230218558-A1 NOVEL THERAPEUTIC USE OF PLEUROMUTILINS HONG KONG KING-FRIEND INDUSTRIAL COMPANY LTD. (CN) 2023-07-13 US disclosed
US-20230174472-A1 THERAPEUTIC USE OF PLEUROMUTILINS HONG KONG KING-FRIEND INDUSTRIAL COMPANY LTD. (CN) 2023-06-08 US disclosed
CN-115286280-B Cement reinforcing agent for cement mill and preparation method thereof 临沂鲁强增强剂有限公司 2023-05-23 CN disclosed
CN-115746277-A Bio-based flame-retardant unsaturated polyester for wood reinforcement modification and preparation and application thereof 华南农业大学 2023-03-07 CN disclosed
CN-115716905-A Multifunctional bio-based water-based acrylate and preparation method and application thereof 广州集泰化工股份有限公司 2023-02-28 CN disclosed
EP-4135682-A1 THERAPEUTIC USE OF PLEUROMUTILINS Nabriva Therapeutics GMBH (AT) 2023-02-22 EP disclosed
CN-1919887-A Copolymer used as water suspension additive and preparation method thereof ARCHITECTURAL TECHNOLOGY RES C (DE) 2007-02-28 CN disclosed
US-6777517-B1 ADDITIVES FOR AQUEOUS SUSPENSIONS OF INORGANIC OR ORGANIC SOLIDS DEGUSSA CONSTRUCTION CHEMICALS GMBH (DE) 2004-08-17 US disclosed
US-4663385-A Process for thickening with copolymers of alkyl poly (oxyalkylene) itaconic di-esters ROHM AND HAAS (US) 1987-05-05 US disclosed
EP-0109820-B1 COPOLYMERS OF ALKYL POLY(OXYALKYLENE) ITACONATES AND THICKENING PROCESSES USING THEM ROHM AND HAAS COMPANY (US) 1987-04-29 EP disclosed
EP-0179941-A1 Transparent blends of polymethylmethacrylate and certain styrene copolymers THE DOW CHEMICAL COMPANY (US) 1986-05-07 EP disclosed
US-4508871-A Transparent blends of polymethylmethacrylate and certain styrene copolymers THE DOW CHEMICAL COMPANY (US) 1985-04-02 US disclosed
EP-0109820-A1 Copolymers of alkyl poly(oxyalkylene) itaconates and thickening processes using them ROHM AND HAAS COMPANY (US) 1984-05-30 EP disclosed
US-4321179-A COPOLYMERIZING A POLYPEROXIDE, UNSATURATED ACID, AND UNSATD COMPOUND; BLEAVAGE; BLOCK POLYMERS NIPPON OIL AND FATS CO., LTD. (JP) 1982-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230312615-A1 METAL-ORGANIC FRAMEWORKS FOR THE STORAGE AND DELIVERY OF HYDROGEN SULFIDE, METHODS OF MAKING AND USES OF SAME PPIF, IL6, SQOR TSHR 3586/4885
US-20230174472-A1 THERAPEUTIC USE OF PLEUROMUTILINS CHRM1, CHRM2, MLN TSHR 1085/4885
US-20230218558-A1 NOVEL THERAPEUTIC USE OF PLEUROMUTILINS MET, CHRM1, MRPS23 TSHR 838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.