Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4185979 | 0.86 | MAOA (0.56) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL1284769 | 0.84 | MAOB (0.57) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL31256797 | 0.83 | LMNA (0.54) | MAOBMAOARAB9ANPC1KDM4E | |
| SCHEMBL22821274 | 0.83 | MAOB (0.52) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL1284616 | 0.83 | MAOB (0.52) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL1619109 | 0.82 | MAOB (0.67) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL30594160 | 0.82 | MAOB (0.67) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL13612673 | 0.80 | MAOA (0.61) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL27625488 | 0.80 | MMP2 (0.67) | MAOBMAOARAB9ANPC1KMT2A | |
| SCHEMBL1284886 | 0.79 | MAOB (0.56) | MAOBMAOARAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800804-B2 | Hybrid galactoside inhibitor of galectins | GALECTO BIOTECH AB | 2020-10-13 | — | — | US | disclosed |
| US-10253059-B2 | Hybrid galactoside inhibitor of galectins | GALECTO BIOTECH AB (DK) | 2019-04-09 | — | — | US | disclosed |
| US-20170349622-A1 | NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS | GALECTO BIOTECH AB (DK) | 2017-12-07 | — | — | US | disclosed |
| US-8383843-B2 | Method for preparing a coumarin compound, chromene compound, and method for preparing a chromene compound | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | CYP3A7, CYP2A7, F7 | MAOB 327/4885MAOA 428/4885RAB9A 1955/4885 |
| US-10253059-B2 | Hybrid galactoside inhibitor of galectins | LGALS1, LGALS3, LGALS2 | MAOB 2981/4885MAOA 3280/4885RAB9A 2430/4885 |
| US-10800804-B2 | Hybrid galactoside inhibitor of galectins | LGALS1, LGALS3, LGALS3BP | MAOB 3264/4885MAOA 3672/4885RAB9A 2461/4885 |
| US-20170349622-A1 | NOVEL HYBRID GALACTOSIDE INHIBITOR OF GALECTINS | LGALS1, LGALS3, LGALS2 | MAOB 3044/4885MAOA 3479/4885RAB9A 2210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.