Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.71 |
| ▸ | MMP3 | P08254 | 6/20 | 0.69 |
| ▸ | MMP2 | P08253 | 7/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410478 | 0.99 | MMP3 (0.71) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL8410486 | 0.94 | MMP3 (0.64) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL4832930 | 0.94 | MMP3 (0.63) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL6328940 | 0.90 | MAPT (0.58) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL1715131 | 0.89 | HDAC1 (0.57) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL7778508 | 0.86 | HDAC1 (0.64) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL7613807 | 0.86 | HDAC1 (0.74) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL8409925 | 0.86 | HDAC1 (0.64) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL13087979 | 0.85 | MMP2 (0.62) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL4275826 | 0.85 | HDAC1 (0.56) | HDAC1HDAC2HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765408-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-12-09 | — | — | EP | disclosed |
| US-9061067-B2 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2015-06-23 | — | — | US | disclosed |
| US-9061067-B2 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2015-06-23 | — | — | US | disclosed |
| US-9061067-B2 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2015-06-23 | — | — | US | disclosed |
| EP-2289560-B1 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | disclosed |
| US-20120088716-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2012-04-12 | — | — | US | disclosed |
| US-20120088716-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2012-04-12 | — | — | US | disclosed |
| US-20120088716-A1 | Polypeptide Protracting Tags | NOVO NORDISK A/S (DK) | 2012-04-12 | — | — | US | disclosed |
| EP-2292272-A2 | Polypeptide protracting tags comprising a tetrazole moiety | NOVO NORDISK A/S (DK) | 2011-03-09 | — | — | EP | disclosed |
| EP-2289560-A2 | Polypeptide protracting tags comprising a tetrazole moiety | NOVO NORDISK A/S (DK) | 2011-03-02 | — | — | EP | disclosed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | disclosed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | disclosed |
| US-20090111730-A1 | Polypeptide protracting tags | NOVO NORDISK A/S (DK) | 2009-04-30 | — | — | US | disclosed |
| EP-1765408-A2 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK A/S (DK) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005667-A2 | POLYPEPTIDE PROTRACTING TAGS COMPRISING A TETRAZOLE MOIETY | NOVO NORDISK A/S (DK) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088716-A1 | Polypeptide Protracting Tags | VIP, FGB, NPPA | HDAC1 3905/4885HDAC2 4662/4885MMP3 1007/4885 |
| US-20090111730-A1 | Polypeptide protracting tags | LNPEP, FGB, ENPEP | HDAC1 4565/4885HDAC2 4801/4885MMP3 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.