Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGMT | P16455 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12598559 | 0.86 | MPO (0.38) | BACE1ALDH1A1 | |
| SCHEMBL12559895 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1518431 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8261348 | 0.80 | MGMT (0.33) | BACE1MGMT | |
| SCHEMBL5924367 | 0.78 | NOS2 (0.46) | BACE1SMN1; SMN2 | |
| SCHEMBL474833 | 0.77 | KCNH2 (0.46) | BACE1ALDH1A1 | |
| SCHEMBL926964 | 0.77 | HSD17B10 (0.45) | ALDH1A1 | |
| SCHEMBL23164498 | 0.76 | KDM4E (0.41) | ALDH1A1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1518262 | 0.75 | HPGD (0.50) | ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16268870 | 0.75 | TBXAS1 (0.41) | PAOXPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9084423-B2 | Inhibition of bacterial biofilms with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-07-21 | — | — | US | disclosed |
| US-8927029-B2 | Inhibition of biofilms in plants with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140079808-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20120328577-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | MELANDER CHRISTIAN (US) | 2012-12-27 | — | — | US | disclosed |
| US-8278340-B2 | Inhibition of biofilms in plants with imidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-10-02 | — | — | US | disclosed |
| US-20090143230-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140079808-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | ITPA, SOD1, ICMT | PAOX 1646/4885BACE1 1191/4885PDE4A 3694/4885 |
| US-20120328577-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | ITPA, SOD1, ICMT | PAOX 1646/4885BACE1 1191/4885PDE4A 3694/4885 |
| US-20140127273-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | O60361, TFPI, BLVRB | PAOX 4632/4885BACE1 3382/4885PDE4A 1717/4885 |
| US-20090143230-A1 | INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES | ITPA, SOD1, ICMT | PAOX 1646/4885BACE1 1191/4885PDE4A 3694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.