SCHEMBL12856348

SCHEMBL12856348

Cc1ccc(N(c2cccc3ccccc23)c2ccc3ccc4c(N(c5ccc(C)cc5)c5cccc6ccccc56)ccc5ccc2c3c54)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
HSD17B10 Q99714 3/20 0.40
CYP1A2 P05177 3/20 0.40
THRB P10828 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
SIGMAR1 Q99720 7/20 0.39
CYP2A6 P11509 2/20 0.39
RAB9A P51151 2/20 0.38
MAOA P21397 2/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
MAPK1 P28482 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17230568 0.91 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL9238715 0.91 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL12744245 0.89 SIGMAR1 (0.44) ALDH1A1CYP1A2L3MBTL1SIGMAR1CYP2A6
SCHEMBL4977548 0.89 SIGMAR1 (0.47) ALDH1A1CYP1A2L3MBTL1TSHRSIGMAR1
SCHEMBL556717 0.87 SIGMAR1 (0.46) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL460778 0.87 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL13320934 0.87 SIGMAR1 (0.46) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL30227851 0.87 SIGMAR1 (0.46) ALDH1A1HPGDHSD17B10CYP1A2THRB
SCHEMBL12744269 0.87 SIGMAR1 (0.43) ALDH1A1CYP1A2L3MBTL1SIGMAR1CYP2A6
SCHEMBL4891181 0.87 SIGMAR1 (0.43) ALDH1A1CYP1A2L3MBTL1SIGMAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9024301-B2 Organic luminescent medium and organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2015-05-05 US disclosed
US-9024301-B2 Organic luminescent medium and organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2015-05-05 US disclosed
US-20130221338-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2013-08-29 US disclosed
US-20130221338-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2013-08-29 US disclosed
US-8450727-B2 Organic luminescent medium and organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2013-05-28 US disclosed
US-8450727-B2 Organic luminescent medium and organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2013-05-28 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-02-24 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
US-7888863-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2011-02-15 US disclosed
EP-2194110-A1 Electroluminescent device using electroluminescent compounds Gracel Display Inc. (KR) 2010-06-09 EP disclosed
US-20090295281-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-12-03 US disclosed
US-20090295281-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-12-03 US disclosed
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-22 US disclosed
EP-2098532-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-09-09 EP disclosed
EP-2085450-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090260686-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, FZD7 ALDH1A1 706/4885HPGD 2654/4885HSD17B10 1527/4885
US-20110042660-A1 ORGANIC LUMINESCENT MEDIUM AND ORGANIC EL DEVICE AOC1, EBPL, CYBA ALDH1A1 277/4885HPGD 1329/4885HSD17B10 3421/4885
US-20090261714-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, ODC1, LEF1 ALDH1A1 19/4885HPGD 3242/4885HSD17B10 1078/4885
US-20090295281-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, LEF1, ODC1 ALDH1A1 19/4885HPGD 3000/4885HSD17B10 1085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.