Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.42 |
| ▸ | MMP9 | P14780 | 10/20 | 0.42 |
| ▸ | MMP13 | P45452 | 9/20 | 0.42 |
| ▸ | MMP3 | P08254 | 9/20 | 0.42 |
| ▸ | MMP7 | P09237 | 8/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12905329 | 0.94 | ALDH1A1 (0.42) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905331 | 0.94 | MMP9 (0.41) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905436 | 0.93 | MMP3 (0.43) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878456 | 0.92 | MMP1 (0.43) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905374 | 0.91 | ALDH1A1 (0.43) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905346 | 0.91 | MMP1 (0.49) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905352 | 0.90 | MMP1 (0.43) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL779102 | 0.88 | MMP1 (0.55) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12942841 | 0.87 | MMP9 (0.44) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905370 | 0.85 | MMP1 (0.50) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110003812-A1 | Human Adam-10 Inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2011-01-06 | — | — | US | disclosed |
| US-20110003812-A1 | Human Adam-10 Inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003812-A1 | Human Adam-10 Inhibitors | ADAM10, MMP20, ADAM9 | MMP1 13/4885MMP9 12/4885MMP13 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.