Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128425 | 0.86 | TERT (0.42) | PSMB5TERTAPPNTSR1MAOA | |
| SCHEMBL129138 | 0.85 | TERT (0.44) | PSMB5TERTAPPMAPTKDM4E | |
| Bromide SCHEMBL9500678 | 0.84 | MAP4K4 (0.40) | TERTAPPNTSR1MAPTEGFR | |
| Bromide SCHEMBL5791833 | 0.83 | TERT (0.43) | PSMB5TERTAPPMAPTKDM4E | |
| SCHEMBL5724692 | 0.83 | PSMB5 (0.43) | PSMB5TERTAPPMAPTKDM4E | |
| Iodide SCHEMBL1470285 | 0.81 | PSMB5 (0.42) | PSMB5TERTAPPMAPTKDM4E | |
| SCHEMBL1470931 | 0.81 | TERT (0.53) | TERTMAPTKDM4EMEN1NPC1 | |
| SCHEMBL12532442 | 0.81 | TERT (0.53) | TERTMAPTKDM4EMEN1NPC1 | |
| SCHEMBL1472495 | 0.80 | TERT (0.40) | TERTAPPMAPTKDM4EMEN1 | |
| Iodide SCHEMBL1470324 | 0.80 | TERT (0.51) | TERTMAPTKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-9765042-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-09-19 | — | — | US | disclosed |
| US-9765042-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-09-19 | — | — | US | disclosed |
| US-9675621-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2017-06-13 | — | — | US | disclosed |
| US-9555043-B2 | High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-01-31 | — | — | US | disclosed |
| US-9555043-B2 | High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2017-01-31 | — | — | US | disclosed |
| US-20160296531-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2016-10-13 | — | — | US | disclosed |
| US-20160251325-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | WISTA LABORATORIES LTD. (SG) | 2016-09-01 | — | — | US | disclosed |
| US-9382220-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2016-07-05 | — | — | US | disclosed |
| US-9242946-B2 | High purity diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2016-01-26 | — | — | US | disclosed |
| US-8691979-B2 | Methods of chemical synthesis of diaminophenothiazinium compounds involving the use of persulfate oxidants | WISTA LABORATORIES LTD. (SG) | 2014-04-08 | — | — | US | disclosed |
| US-8440821-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2013-05-14 | — | — | US | disclosed |
| US-20120058995-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | WISTA LABORATORIES LTD. (SG) | 2012-03-08 | — | — | US | disclosed |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. | 2011-12-01 | — | — | US | disclosed |
| US-7956183-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2011-06-07 | — | — | US | disclosed |
| US-20110021510-A1 | METHODS OF CHEMICAL SYNTHESIS AND PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | WISTA LABORATORIES LTD. | 2011-01-27 | — | — | US | disclosed |
| US-7790881-B2 | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (MTC) | WISTA LABORATORIES LTD. (SG) | 2010-09-07 | — | — | US | disclosed |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2009-10-15 | — | — | US | disclosed |
| US-20080207603-A1 | Methods of Chemical Synthesis and Purification of Diaminophenothiazinium Compounds Including Methylthioninium Chloride (Mtc) | WISTA LABORATORIES LTD. | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | TRPV1 3884/4885PSMB5 333/4885TERT 600/4885 |
| US-20080207603-A1 | Methods of Chemical Synthesis and Purification of Diaminophenothiazinium Compounds Including Methylthioninium Chloride (Mtc) | MGMT, MAPT, CRBN | TRPV1 3593/4885PSMB5 2009/4885TERT 10/4885 |
| US-20160251325-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | GNMT, MT-ND5, CMPK1 | TRPV1 4055/4885PSMB5 1982/4885TERT 233/4885 |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | PARK7, SNCA, GRN | TRPV1 4554/4885PSMB5 1089/4885TERT 96/4885 |
| US-20120058995-A1 | METHODS OF CHEMICAL SYNTHESIS OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INVOLVING THE USE OF PERSULFATE OXIDANTS | TST, TPMT, MGMT | TRPV1 4387/4885PSMB5 424/4885TERT 61/4885 |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MMAB, MB, ABCB7 | TRPV1 3337/4885PSMB5 565/4885TERT 743/4885 |
| US-20110021510-A1 | METHODS OF CHEMICAL SYNTHESIS AND PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS INCLUDING METHYLTHIONINIUM CHLORIDE (MTC) | MGMT, TST, MAPT | TRPV1 3869/4885PSMB5 1480/4885TERT 11/4885 |
| US-20160296531-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | TRPV1 3884/4885PSMB5 333/4885TERT 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.