Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968441 | 0.95 | KDM4E (0.44) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12799828 | 0.92 | MAPT (0.44) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12799862 | 0.92 | MAPT (0.44) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12969344 | 0.90 | ALOX5 (0.46) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12968447 | 0.90 | ALOX5 (0.46) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12969181 | 0.89 | HPRT1 (0.46) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL24171335 | 0.88 | PLA2G2A (0.47) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12968451 | 0.88 | MEN1 (0.43) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL12799821 | 0.88 | ALOX5 (0.46) | KDM4EMAPTHPGDALDH1A1CYP3A4 | |
| SCHEMBL24393840 | 0.86 | ALOX5 (0.49) | KDM4EMAPTHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640252-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | UDC Ireland Limited (IE) | 2020-04-22 | — | — | EP | disclosed |
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2019-10-01 | — | — | US | disclosed |
| US-20190273211-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | UDC IRELAND LTD (IE) | 2019-09-05 | — | — | US | disclosed |
| US-9806270-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2017-10-31 | — | — | US | disclosed |
| WO-2012130709-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2012-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | EIF4A1, ITPR2, ITPR1 | KDM4E 1166/4885MAPT 1159/4885HPGD 1129/4885 |
| US-20190273211-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | PAH, NISCH, KCNH1 | KDM4E 1128/4885MAPT 1665/4885HPGD 486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.