Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13001991 | 0.94 | TRPA1 (0.62) | PDE4BTRPA1MTNR1AXDHSMN1; SMN2 | |
| SCHEMBL433948 | 0.85 | ALDH1A1 (0.64) | PDE4BSMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL22916227 | 0.82 | PDE4B (0.59) | PDE4BSMN1; SMN2MAPTALDH1A1CA12 | |
| SCHEMBL22916132 | 0.82 | PDE4B (0.59) | PDE4BSMN1; SMN2MAPTALDH1A1CA12 | |
| 3,4-Dimethoxy Cinnamaldehyde SCHEMBL3000359 | 0.82 | XDH (0.72) | TRPA1MTNR1AXDHSMN1; SMN2MAPT | |
| 3,4-Dimethoxy Cinnamaldehyde SCHEMBL563071 | 0.82 | XDH (0.72) | TRPA1MTNR1AXDHSMN1; SMN2MAPT | |
| SCHEMBL20117684 | 0.81 | FDPS (0.65) | PDE4BSMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL29924333 | 0.80 | FDPS (0.69) | PDE4BSMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL1231147 | 0.80 | FDPS (0.69) | PDE4BSMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL25201579 | 0.79 | PDE4B (0.60) | PDE4BTRPA1MTNR1AXDHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839640-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2017-12-12 | — | — | US | disclosed |
| WO-2010144959-A1 | ANALOGUES OF ANTI-FIBROTIC AGENTS | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2010-12-23 | — | — | WO | disclosed |