Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | ALAD | P13716 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997985 | 0.92 | — | — | |
| SCHEMBL717099 | 0.86 | EGLN1 (0.34) | ALDH1A1 | |
| SCHEMBL7862234 | 0.78 | MAPT (0.52) | ALDH1A1CYP2A6CA2CA9TSHR | |
| SCHEMBL1673427 | 0.76 | ALDH1A1 (0.73) | ALDH1A1MAPK1CYP2A6CA12CA2 | |
| SCHEMBL68094 | 0.76 | ALDH1A1 (0.73) | ALDH1A1MAPK1CYP2A6CA12CA2 | |
| SCHEMBL12302096 | 0.76 | ALDH1A1 (0.73) | ALDH1A1MAPK1CYP2A6CA12CA2 | |
| SCHEMBL92056 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPK1CA12CA2CA9 | |
| SCHEMBL8974493 | 0.75 | NPC1 (0.41) | ALDH1A1MAPK1CA2NPC1NFKB1 | |
| SCHEMBL13410607 | 0.74 | ACHE (0.42) | ALDH1A1CA2CA9NPC1RAB9A | |
| SCHEMBL10295281 | 0.74 | ESR1 (0.58) | ALDH1A1CA12CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8449794-B2 | Non-resonant two-photon absorption recording material and non-resonant two-photon absorption compound | FUJIFILM CORPORATION (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20120319059-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | FUJIFILM CORPORATION (JP) | 2012-12-20 | — | — | US | disclosed |
| US-20100330496-A1 | SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN | FUJIFILM CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100078607-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | FUJIFILM CORPORATION (JP) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100078607-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | SIGMAR1, SFN, CRY2 | ALDH1A1 2184/4885MAPK1 4086/4885CYP2A6 2966/4885 |
| US-20120319059-A1 | NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND | CRY2, KCNJ2, NONO | ALDH1A1 1118/4885MAPK1 2688/4885CYP2A6 3216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.