Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL717099 | 0.88 | EGLN1 (0.34) | ALDH1A1CYP3A4TDP1 | |
| Biphenyl SCHEMBL11354502 | 0.84 | MMP3 (0.58) | ALDH1A1TDP1MMP3BCL2L1CA1 | |
| SCHEMBL244994 | 0.82 | — | — | |
| SCHEMBL31148860 | 0.79 | — | — | |
| SCHEMBL1810851 | 0.79 | CA4 (0.35) | ALDH1A1TDP1CA1CA2CA9 | |
| SCHEMBL1807521 | 0.79 | CA4 (0.35) | ALDH1A1CYP1A2TDP1CA1CA2 | |
| Hydrochloric Acid SCHEMBL1304764 | 0.79 | CA4 (0.35) | ALDH1A1TDP1CA1CA2CA9 | |
| SCHEMBL3734578 | 0.79 | CA4 (0.35) | ALDH1A1TDP1CA1CA2CA9 | |
| SCHEMBL5589968 | 0.79 | CA4 (0.35) | ALDH1A1TDP1CA1CA2CA9 | |
| SCHEMBL13019496 | 0.79 | RAB9A (0.60) | ALDH1A1MAPK1TDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014838-B | Compound and preparation method and application thereof | 山东师范大学 | 2024-03-19 | — | — | CN | claimed |
| CN-113956232-B | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-09-16 | — | — | CN | claimed |
| CN-114014838-A | Compound and preparation method and application thereof | 山东师范大学 | 2022-02-08 | — | — | CN | claimed |
| CN-113956232-A | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-01-21 | — | — | CN | claimed |
| CN-118772206-A | Isocyanorhodium (I) zwitterionic complex, preparation method thereof, micelle, nano diagnosis and treatment probe and anticancer drug | 兰州大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-114014838-B | Compound and preparation method and application thereof | 山东师范大学 | 2024-03-19 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-113956232-B | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-114014838-A | Compound and preparation method and application thereof | 山东师范大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113956232-A | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-01-21 | — | — | CN | disclosed |
| US-20170174582-A1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | DOW AGROSCIENCES LLC | 2017-06-22 | — | — | US | disclosed |
| US-9624193-B2 | Cyclic azine derivatives, processes for producing these, and organic electroluminescent element containing these as component | TOSOH CORPORATION (JP) | 2017-04-18 | — | — | US | disclosed |
| US-8212056-B2 | Ligands for transition-metals and methods of use | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2012-07-03 | — | — | US | disclosed |
| US-8128848-B2 | Diketopyrrolopyrrole pigment composition for use in color filters | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-03-06 | — | — | US | disclosed |
| US-20110046380-A1 | METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-24 | — | — | US | disclosed |
| US-20110028718-A1 | PARACYCLOPHANE-BASED LIGANDS, THEIR PREPARATION AND USE IN CATALYSIS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2011-02-03 | — | — | US | disclosed |
| US-20100219384-A1 | Diketopyrrolopyrrole Pigment Composition For Use In Color Filters | CLARIANT FINANCE (BVI) LIMITED (VG) | 2010-09-02 | — | — | US | disclosed |
| US-20090326243-A1 | Ligands for transition-metals and methods of use | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2009-12-31 | — | — | US | disclosed |
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| US-7332499-B2 | Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides | MERCK & CO., INC. (US) | 2008-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028718-A1 | PARACYCLOPHANE-BASED LIGANDS, THEIR PREPARATION AND USE IN CATALYSIS | C1S, XDH, CYCS | ALDH1A1 2148/4885TAAR1 1342/4885CYP1A2 22/4885 |
| US-20170174582-A1 | METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND | PAH, TYR, AHR | ALDH1A1 1437/4885TAAR1 724/4885CYP1A2 320/4885 |
| US-20090326243-A1 | Ligands for transition-metals and methods of use | PDK4, PDXK, PDK3 | ALDH1A1 1267/4885TAAR1 1450/4885CYP1A2 776/4885 |
| US-20110046380-A1 | METHOD FOR PRODUCING UNSATURATED ORGANIC COMPOUND | NIT2, NOS1, CHRM1 | ALDH1A1 948/4885TAAR1 46/4885CYP1A2 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.