Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18585998 | 0.81 | ALDH1A1 (0.36) | ALDH1A1LMNALOXL2KDM4EL3MBTL1 | |
| SCHEMBL4593796 | 0.81 | RECQL (0.47) | ALDH1A1LMNALOXL2KDM4EL3MBTL1 | |
| SCHEMBL13040670 | 0.78 | ALDH1A1 (0.35) | ALDH1A1LMNALOXL2KDM4EL3MBTL1 | |
| SCHEMBL4334724 | 0.77 | KDM4E (0.41) | ALDH1A1LMNALOXL2KDM4EL3MBTL1 | |
| SCHEMBL6619720 | 0.74 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EL3MBTL1GLA | |
| SCHEMBL4594365 | 0.72 | ALDH1A1 (0.34) | ALDH1A1LMNALOXL2KDM4EHPGD | |
| SCHEMBL4594579 | 0.72 | AKT1 (0.36) | ALDH1A1LMNAKDM5AKDM4C | |
| SCHEMBL31068662 | 0.71 | CCR1 (0.63) | ALDH1A1LMNALOXL2KDM4EESR1 | |
| SCHEMBL1681724 | 0.71 | CCR1 (0.44) | LOXL2KDM4EESR1KDM4CRECQL | |
| SCHEMBL3560036 | 0.71 | KDM4E (0.47) | ALDH1A1LMNAKDM4EL3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | NOS2, NOS3, NOS1 | ALDH1A1 1292/4885LMNA 4326/4885LOXL2 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.