Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CCR1 | P32246 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL6839921 | 0.91 | ALDH1A1 (0.50) | ALDH1A1LMNACCR1CCR5CCR8 | |
| Propanol SCHEMBL6771763 | 0.88 | ALDH1A1 (0.48) | ALDH1A1LMNACCR1CCR5CCR8 | |
| SCHEMBL4648753 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNACCR1CCR5CCR8 | |
| SCHEMBL3560036 | 0.79 | KDM4E (0.47) | ALDH1A1LMNACCR1CCR5CCR8 | |
| SCHEMBL7211888 | 0.78 | PTGS2 (0.59) | ALDH1A1LMNAKDM4EMAPTHPGD | |
| SCHEMBL18586126 | 0.76 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30839382 | 0.76 | CCR1 (0.52) | ALDH1A1LMNACCR1CCR5CCR8 | |
| SCHEMBL18585998 | 0.75 | ALDH1A1 (0.36) | ALDH1A1LMNACCR1CCR5CCR8 | |
| SCHEMBL2562409 | 0.75 | ALDH1A1 (0.40) | ALDH1A1LMNACCR1CCR5CCR8 | |
| SCHEMBL4593796 | 0.75 | RECQL (0.47) | ALDH1A1LMNAKDM4EMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110761-A1 | POTENT HUMAN NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | Northwestern University (US) | 2023-01-04 | — | — | EP | disclosed |
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
| CN-1546470-A | 6-phenylpyridyl-2-amine derivatives | ������ҩ������˾ | 2004-11-17 | — | — | CN | disclosed |
| EP-1471055-A1 | 6-phenylpyridyl-2-amine derivatives | PFIZER INC. (US) | 2004-10-27 | — | — | EP | disclosed |
| CN-1168719-C | 6-phenylpyridin-2-ylamine derivatives, pharmaceutical compositions and uses | ������ҩ������˾ | 2004-09-29 | — | — | CN | disclosed |
| EP-0891332-B1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6465491-B2 | NITRIC OXIDE SYNTHASE INHIBITOR; NERVOUS SYSTEM DISORDERS | PFIZER INC. | 2002-10-15 | — | — | US | disclosed |
| US-20010034348-A1 | 6-phenylpyridyl-2-amine derivatives | LOWE JOHN A (US) | 2001-10-25 | — | — | US | disclosed |
| US-6235747-B1 | NITRIC OXIDE SYNTHASE INHIBITOR | PFIZER INC. | 2001-05-22 | — | — | US | disclosed |
| EP-1095020-A1 | 2-AMINOPYRIDINE ERIVATIVES, THEIR USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000002860-A1 | 2-AMINOPYRIDINE ERIVATIVES, THEIR USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-01-20 | — | — | WO | disclosed |
| CN-1215391-A | 6-phenylpyridyl-2-amine derivatives | PFIZER (US) | 1999-04-28 | — | — | CN | disclosed |
| EP-0891332-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036871-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1997-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034348-A1 | 6-phenylpyridyl-2-amine derivatives | NOS2, NOS3, NOS1 | ALDH1A1 1322/4885LMNA 2447/4885CCR1 4234/4885 |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | ADRB2, ADRB1, ADRA2C | ALDH1A1 650/4885LMNA 999/4885CCR1 3786/4885 |
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | NOS2, NOS3, NOS1 | ALDH1A1 1292/4885LMNA 4326/4885CCR1 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.