Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22045060 | 0.97 | HSD11B1 (0.34) | HSD11B1HSD11B2ALDH1A1CYP2B6SIGMAR1 | |
| SCHEMBL8827280 | 0.79 | ALDH1A1 (0.45) | HSD11B1HSD11B2ALDH1A1CYP2B6SIGMAR1 | |
| SCHEMBL20440205 | 0.78 | CA2 (0.36) | SIGMAR1HPGD | |
| SCHEMBL3635465 | 0.77 | L3MBTL1 (0.37) | HSD11B1HSD11B2ALDH1A1CYP2B6SIGMAR1 | |
| Acetic Acid SCHEMBL7359984 | 0.77 | ALDH1A1 (0.39) | HSD11B1HSD11B2ALDH1A1CYP2B6SMN1; SMN2 | |
| SCHEMBL12758500 | 0.77 | GAA (0.35) | HSD11B1HSD11B2ALDH1A1CYP2B6SIGMAR1 | |
| SCHEMBL23717930 | 0.77 | SIGMAR1 (0.45) | SIGMAR1MEN1KMT2A | |
| SCHEMBL3661207 | 0.76 | ALDH1A1 (0.42) | HSD11B1HSD11B2ALDH1A1CYP2B6SIGMAR1 | |
| SCHEMBL22045061 | 0.75 | CA2 (0.38) | HSD11B1ALDH1A1SIGMAR1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL9698155 | 0.75 | L3MBTL1 (0.35) | HSD11B1HSD11B2ALDH1A1CYP2B6SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180029970-A1 | ACRYLIC ADHESIVE COMPOSITION FROM PROTECTED PHOTOCROSSLINKING AGENTS | 3M INNOVATIVE PROPERTIES COMPANY | 2018-02-01 | — | — | US | disclosed |
| US-7838110-B2 | Aziridine-functional photoactive crosslinking compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-11-23 | — | — | US | disclosed |
| US-20100137469-A1 | AZIRIDINE-FUNCTIONAL PHOTOACTIVE CROSSLINKING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY | 2010-06-03 | — | — | US | disclosed |
| US-7465726-B2 | Substituted pyrrolo[2.3-B]pyridines | OSI PHARMACEUTICALS, INC. (US) | 2008-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180029970-A1 | ACRYLIC ADHESIVE COMPOSITION FROM PROTECTED PHOTOCROSSLINKING AGENTS | DCLRE1A, RAD51, COL2A1 | HSD11B1 4834/4885HSD11B2 4780/4885ALDH1A1 316/4885 |
| US-20100137469-A1 | AZIRIDINE-FUNCTIONAL PHOTOACTIVE CROSSLINKING COMPOUNDS | PTMA, PAM, AAAS | HSD11B1 3277/4885HSD11B2 3008/4885ALDH1A1 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.