Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860834 | 0.87 | GFER (0.42) | TAAR1MAOBCYP2A6HTR3ASLC6A2 | |
| SCHEMBL2135113 | 0.84 | TAAR1 (0.68) | TAAR1IDO1MAOBAOC3LMNA | |
| SCHEMBL2451061 | 0.83 | TAAR1 (0.54) | TAAR1IDO1MAOBAOC3HTR3E | |
| SCHEMBL8972135 | 0.81 | IGF1R (0.55) | TAAR1IDO1MAOBAOC3HTR3E | |
| Chlorobenzene SCHEMBL27596760 | 0.81 | TSHR (0.55) | TAAR1MAOBCYP2A6ALOX15HTR2A | |
| SCHEMBL16663974 | 0.80 | TAAR1 (0.56) | TAAR1IDO1MAOBAOC3LMNA | |
| SCHEMBL18050371 | 0.79 | TAAR1 (0.62) | TAAR1IDO1MAOBAOC3LMNA | |
| SCHEMBL9552844 | 0.79 | MAOB (0.46) | TAAR1MAOB | |
| SCHEMBL9192375 | 0.79 | CA2 (0.42) | TAAR1MAOBLMNACYP2A6HTR3A | |
| SCHEMBL9553020 | 0.79 | MAOB (0.46) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11919854-B2 | P2RX7 modulators in therapy | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-03-05 | — | — | US | claimed |
| CN-112512520-A | P2RX7 modulators in therapy | 国家科学研究中心 | 2021-03-16 | — | — | CN | claimed |
| EP-3773557-A1 | P2RX7 MODULATORS IN THERAPY | Centre national de la recherche scientifique (FR) | 2021-02-17 | — | — | EP | claimed |
| US-20210017131-A1 | P2RX7 MODULATORS IN THERAPY | JUNIA (FR) | 2021-01-21 | — | — | US | claimed |
| WO-2020196767-A1 | FOAMED MULTILAYER SHEET, UNFOAMED MULTILAYER SHEET, FUNGICIDE, AND RESIN COMPOSITION | 大日本印刷株式会社 | 2020-10-01 | — | — | WO | claimed |
| CN-111362932-A | Isothiazole oxadiazole amide derivatives and preparation method and application thereof | 南开大学 | 2020-07-03 | — | — | CN | claimed |
| WO-2019185868-A1 | P2RX7 MODULATORS IN THERAPY | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2019-10-03 | — | — | WO | claimed |
| US-20150210625-A1 | PROCESSES FOR THE PREPARATION OF 5-HT2C RECEPTOR AGONISTS | ARENA PHARMACEUTICALS, INC. | 2015-07-30 | — | — | US | claimed |
| US-8952197-B2 | Processes for the preparation of 5-HT2C receptor agonists | ARENA PHARMACEUTICALS, INC. (US) | 2015-02-10 | — | — | US | claimed |
| CN-102648170-A | Processes for the preparation of 5-HT2C receptor agonists | ARENA PHARM INC | 2012-08-22 | — | — | CN | claimed |
| WO-2001014879-A1 | 4-UNSUBSTITUTED DIHYDROISOQUINOLINONE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-03-01 | — | — | WO | claimed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| EP-0718407-A1 | Intermediates for the synthesis of eliprodil enantiomers and process for their preparation | SYNTHELABO (FR) | 1996-06-26 | — | — | EP | claimed |
| US-5401766-A | Hypotensive agents with vasodilation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | claimed |
| EP-0328160-B1 | Amino acid derivatives, process to prepare them, composition containing them and their use | HOECHST AG (DE) | 1994-05-04 | — | — | EP | claimed |
| US-5192783-A | Fungicides for plants | ROHM AND HAAS COMPANY (US) | 1993-03-09 | — | — | US | claimed |
| EP-0046953-B1 | AMINO ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-06 | — | — | EP | claimed |
| EP-0328160-A1 | Amino acid derivatives, process to prepare them, composition containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | claimed |
| EP-0278530-A2 | Amino acid derivatives, process for their preparation, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017131-A1 | P2RX7 MODULATORS IN THERAPY | P2RX3, P2RX7, P2RX2 | TAAR1 408/4885IDO1 1464/4885MAOB 3007/4885 |
| US-11919854-B2 | P2RX7 modulators in therapy | P2RX7, P2RX2, P2RX1 | TAAR1 384/4885IDO1 1389/4885MAOB 3226/4885 |
| US-20150210625-A1 | PROCESSES FOR THE PREPARATION OF 5-HT2C RECEPTOR AGONISTS | HTR2C, HTR3C, HTR5A | TAAR1 155/4885IDO1 479/4885MAOB 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.