Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13024610 | 0.89 | P2RY6 (0.67) | P2RY6SLC5A2GBA1ITPR1CA12 | |
| SCHEMBL13078102 | 0.89 | ESR1 (0.56) | P2RY6SLC5A2USP2ESR1CA12 | |
| SCHEMBL13066051 | 0.88 | P2RY6 (0.46) | P2RY6SLC5A2GBA1ITPR1ABCB1 | |
| SCHEMBL92964 | 0.88 | P2RY6 (0.49) | P2RY6GBA1ITPR1ABCB1USP2 | |
| SCHEMBL14597210 | 0.87 | P2RY6 (0.51) | P2RY6SLC5A2GBA1ITPR1MAPT | |
| SCHEMBL13066052 | 0.87 | SLC5A2 (0.45) | P2RY6SLC5A2USP2ESR1CA12 | |
| SCHEMBL10293892 | 0.84 | ESR1 (0.56) | P2RY6SLC5A2USP2ESR1CA12 | |
| SCHEMBL10293948 | 0.84 | P2RY6 (0.46) | P2RY6SLC5A2GBA1ITPR1USP2 | |
| SCHEMBL13066099 | 0.83 | ESR1 (0.52) | P2RY6SLC5A2USP2ESR1CA12 | |
| SCHEMBL13065979 | 0.82 | P2RY6 (0.42) | P2RY6SLC5A2USP2ESR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | APPLERA CORPORATION (US) | 2010-11-04 | — | — | US | disclosed |
| US-7825237-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2010-11-02 | — | — | US | disclosed |
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | Life Technologies Corporation (US) | 2010-02-04 | — | — | US | disclosed |
| US-7595162-B2 | Methods of labeling polynucleotides with energy transfer dyes | APPLIED BIOSYSTEMS, LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090118485-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLIED BIOSYSTEMS INC. (US) | 2009-05-07 | — | — | US | disclosed |
| US-7449298-B2 | Methods of analyzing polynucleotides employing energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449149-B2 | Kits useful for sequencing nucleic acids | APPLIED BIOSYSTEMS INC. (US) | 2008-11-11 | — | — | US | disclosed |
| US-20080268509-A1 | METHODS OF LABELING POLYNUCLEOTIDES WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2008-10-30 | — | — | US | disclosed |
| US-7432058-B2 | Methods of labeling nucleic acids with energy transfer dyes | APPLERA CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-7423140-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLIED BIOSYSTEMS INC. (US) | 2008-09-09 | — | — | US | disclosed |
| US-7399854-B2 | Regents labeled with energy transfer dyes | APPLERA CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |
| US-7388092-B2 | Oligonucleotides and analogs labeled with energy transfer dyes | APPLERA CORPORATION (US) | 2008-06-17 | — | — | US | disclosed |
| US-20070212709-A1 | Non-nucleosidic linker linking xanthene donor to 4,7-dichlororhodamine acceptor; | APPLERA CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070207477-A1 | KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS | APPLERA CORPORATION (US) | 2007-09-06 | — | — | US | disclosed |
| US-20070161026-A1 | REGENTS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070161027-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-12 | — | — | US | disclosed |
| US-20070154924-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-20070154925-A1 | METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES | APPLERA CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-7169939-B2 | Energy transfer dyes with enhanced fluorescence | APPLERA CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154924-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RPS28 | P2RY6 4215/4885SLC5A2 2377/4885GBA1 1741/4885 |
| US-20100280246-A1 | ENERGY TRANSFER DYES WITH ENHANCED FLUORESCENCE | SLC25A21, ZCCHC8, ZDHHC7 | P2RY6 4446/4885SLC5A2 2548/4885GBA1 2138/4885 |
| US-20100029923-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RPS28 | P2RY6 4215/4885SLC5A2 2377/4885GBA1 1741/4885 |
| US-20070212709-A1 | Non-nucleosidic linker linking xanthene donor to 4,7-dichlororhodamine acceptor; | DCLRE1A, SLC25A21, DIMT1 | P2RY6 4205/4885SLC5A2 3732/4885GBA1 1748/4885 |
| US-20070161027-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RTCB | P2RY6 4273/4885SLC5A2 2583/4885GBA1 1862/4885 |
| US-20070161026-A1 | REGENTS LABELED WITH ENERGY TRANSFER DYES | SOAT1, GFPT1, CBR3 | P2RY6 4094/4885SLC5A2 2122/4885GBA1 2254/4885 |
| US-20070207477-A1 | KITS USEFUL FOR SEQUENCING NUCLEIC ACIDS | RNGTT, POLRMT, MRM1 | P2RY6 4397/4885SLC5A2 3719/4885GBA1 2274/4885 |
| US-20090118485-A1 | OLIGONUCLEOTIDES AND ANALOGS LABELED WITH ENERGY TRANSFER DYES | RBM28, TRDMT1, RTCB | P2RY6 4273/4885SLC5A2 2583/4885GBA1 1862/4885 |
| US-20070154925-A1 | METHODS OF ANALYZING POLYNUCLEOTIDES EMPLOYING ENERGY TRANSFER DYES | POLRMT, NOP2, NSUN3 | P2RY6 3047/4885SLC5A2 3477/4885GBA1 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.