Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 2/20 | 0.71 |
| ▸ | DRD1 | P21728 | 4/20 | 0.50 |
| ▸ | DRD5 | P21918 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24964880 | 0.97 | MAOA (0.68) | MAOAMAOBDRD1DRD5DRD3 | |
| Bromide SCHEMBL2646357 | 0.97 | MAOA (0.68) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL24227957 | 0.92 | DRD1 (0.62) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL1649346 | 0.86 | MAOA (0.56) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL29390912 | 0.84 | MAOA (1.00) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL98108 | 0.84 | MAOA (1.00) | MAOAMAOBDRD1DRD5DRD3 | |
| Hydrochloric Acid SCHEMBL23501375 | 0.82 | MAOA (1.00) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL14573056 | 0.81 | MAOA (0.56) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL1950767 | 0.80 | MAOA (0.75) | MAOAMAOBDRD1DRD5DRD3 | |
| SCHEMBL4320673 | 0.80 | MAOA (0.91) | MAOAMAOBDRD1DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917927-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2021-12-08 | — | — | EP | claimed |
| CN-113365990-A | Polymorphs of methylisoindin and improved formulations of methylisoindin | 纳特罗根治疗国际有限公司 | 2021-09-07 | — | — | CN | claimed |
| WO-2020156323-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-08-06 | — | — | WO | claimed |
| US-20130316279-A1 | Organic Semiconductor Composition | CENTRAL GLASS COMPANY, LIMITED (JP) | 2013-11-28 | — | — | US | claimed |
| CN-100488958-C | 3-substituted-4-pyrimidone derivatives | MITSUBISHI PHARMA CORP SANOFI (JP) | 2009-05-20 | — | — | CN | claimed |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. | 2008-08-21 | — | — | US | claimed |
| US-12552758-B2 | Inhibitors of MLH1 and/or PMS2 for cancer treatment | Neophore Limited (GB) | 2026-02-17 | — | — | US | disclosed |
| CN-115003677-B | Compounds having inhibitory activity against KRAS G12D mutations | 大鹏药品工业株式会社 | 2024-08-27 | — | — | CN | disclosed |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Université de Montréal (CA) | 2024-07-18 | — | — | US | disclosed |
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| WO-2024132801-A1 | XANTHENE COMPOUNDS HAVING A WAVELENGTH IN THE RANGE FROM 650 TO 1200 NM | BASF SE (DE) | 2024-06-27 | — | — | WO | disclosed |
| EP-0186187-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1992-02-26 | — | — | EP | disclosed |
| EP-0452987-A1 | Isoindoline derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |
| US-4954590-A | SUBJECTING ISOINDOLINE ISOINDOLE COMPOUND TO OXIDATIVE POLYMERIZATION; ELECTROCONDUCTIVE POLYMER | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4833231-A | Polymer having isoindole structure | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0248915-A1 | POLYMERS HAVING ISOINDOLE STRUCTURE AND PROCESS FOR THEIR PREPARATION | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1987-12-16 | — | — | EP | disclosed |
| US-4677100-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-06-30 | — | — | US | disclosed |
| EP-0186187-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037641-B2 | Modified nucleotide reagents | POLL, POLN, POLM | MAOA 2805/4885MAOB 2201/4885DRD1 2308/4885 |
| US-12552758-B2 | Inhibitors of MLH1 and/or PMS2 for cancer treatment | MSH2, PMS2, MSH6 | MAOA 2701/4885MAOB 2187/4885DRD1 3880/4885 |
| US-20080200454-A1 | CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S | CTSS, CTSK, CTSZ | MAOA 2112/4885MAOB 1496/4885DRD1 3655/4885 |
| US-20240239801-A1 | PYRIMIDO[5,4,D]PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NRAS, BRAF, KRAS | MAOA 3729/4885MAOB 2309/4885DRD1 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.