Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1985922 | 0.88 | AHR (0.58) | AHRALOX5TGM2CES1CA12 | |
| SCHEMBL29689592 | 0.88 | AHR (0.58) | AHRALOX5TGM2CES1CA12 | |
| Benzene SCHEMBL28149598 | 0.84 | AHR (0.54) | AHRALOX5TGM2CES1CA12 | |
| SCHEMBL46736 | 0.81 | AHR (0.56) | AHRALOX5TGM2CES1CA12 | |
| SCHEMBL13833013 | 0.79 | ALOX5 (0.65) | AHRALOX5LMNAMAPTHTR2B | |
| SCHEMBL30839233 | 0.79 | ALOX5 (0.65) | AHRALOX5LMNAMAPTHTR2B | |
| SCHEMBL28731967 | 0.74 | AHR (0.47) | AHRALOX5 | |
| SCHEMBL19417332 | 0.71 | AHR (0.44) | AHRLMNAMAPTHTTBLM | |
| SCHEMBL10171010 | 0.70 | TGM2 (0.54) | AHRTGM2CES1CA12CA1 | |
| SCHEMBL30869584 | 0.70 | AHR (0.42) | AHRALOX5TGM2CES1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842823-B2 | Fluorogenic probes for reactive oxygen species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-11-30 | — | — | US | disclosed |
| US-20070141658-A1 | Fluorogenic probes for reactive oxygen species | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141658-A1 | Fluorogenic probes for reactive oxygen species | PRDX1, GPX1, GPX4 | AHR 1219/4885ALOX5 905/4885TGM2 3448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.