SCHEMBL13085565

SCHEMBL13085565

CNC(=O)c1cc(S(C)(=O)=O)cc(C)c1NC(=O)c1cc(Cn2nnnc2C(F)(F)F)nn1-c1ccccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
RXRA P19793 4/20 0.34
NR1H2 P55055 4/20 0.34
NR1H3 Q13133 4/20 0.34
F10 P00742 9/20 0.34
F2 P00734 2/20 0.34
NTRK1 P04629 2/20 0.32
IDH1 O75874 1/20 0.32
STIM1 Q13586 1/20 0.31
ORAI1 Q96D31 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL685553 0.88 NTRK1 (0.32) NTRK1IDH1MEN1KMT2A
SCHEMBL10076317 0.88 SLC2A1 (0.36) NTRK1IDH1MEN1KMT2A
SCHEMBL13085374 0.87 RXRA (0.36) ALDH1A1LMNARXRANR1H2NR1H3
SCHEMBL13085510 0.84 NTRK1 (0.34) F10NTRK1
SCHEMBL13085481 0.83 L3MBTL1 (0.38) ALDH1A1NTRK1
SCHEMBL13085380 0.83 ALDH1A1 (0.36) ALDH1A1NTRK1
SCHEMBL10076312 0.82 SLC2A1 (0.34) NTRK1IDH1MEN1KMT2A
SCHEMBL13349862 0.82 P2RX7 (0.32) NTRK1IDH1MEN1KMT2A
SCHEMBL13085517 0.82 NTRK1 (0.40) ALDH1A1LMNANTRK1MEN1KMT2A
SCHEMBL12051839 0.81 SLC2A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 ALDH1A1 3779/4885LMNA 3763/4885RXRA 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.