Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13085699 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EEDNRBEDNRACYP1A2 | |
| SCHEMBL379312 | 0.76 | L3MBTL1 (0.40) | ALDH1A1KDM4ECYP1A2PDE4APDE4B | |
| SCHEMBL4049194 | 0.76 | NOS3 (0.34) | — | |
| SCHEMBL13085664 | 0.76 | SORD (0.35) | LMNACRHR1 | |
| SCHEMBL12120832 | 0.74 | NOS2 (0.42) | KDM4E | |
| SCHEMBL25843255 | 0.74 | ESR1 (0.32) | EDNRBEDNRA | |
| SCHEMBL21646563 | 0.73 | SMN1; SMN2 (0.35) | ALDH1A1KDM4EEDNRBEDNRACYP1A2 | |
| SCHEMBL13085710 | 0.73 | POLQ (0.39) | ALDH1A1KDM4ECYP1A2LMNASMN1; SMN2 | |
| SCHEMBL30147946 | 0.73 | SMN1; SMN2 (0.35) | ALDH1A1KDM4EEDNRBEDNRACYP1A2 | |
| SCHEMBL11993557 | 0.72 | VSIR (0.35) | ALDH1A1KDM4ECYP1A2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816522-B2 | Triazolone derivatives | EISAI CO., LTD. (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20080015199-A1 | Triazolone derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015199-A1 | Triazolone derivatives | F3, F12, F2 | ALDH1A1 710/4885KDM4E 3720/4885ABCB11 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.