Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | RBP4 | P02753 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12236475 | 0.83 | RBP4 (0.56) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1088258 | 0.82 | L3MBTL1 (0.77) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13128801 | 0.81 | RBP4 (0.61) | L3MBTL1RBP4EPHX2 | |
| SCHEMBL28928977 | 0.79 | L3MBTL1 (0.63) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13128807 | 0.79 | GAA (0.49) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL22972208 | 0.78 | L3MBTL1 (0.75) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2224365 | 0.77 | L3MBTL1 (0.69) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7943306 | 0.77 | L3MBTL1 (1.00) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL23407905 | 0.76 | CES2 (0.46) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13744784 | 0.76 | L3MBTL1 (0.73) | L3MBTL1RBP4CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249098-A1 | OXYPIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2010-09-30 | — | — | US | disclosed |
| US-20100249098-A1 | OXYPIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2010-09-30 | — | — | US | disclosed |
| WO-2009045313-A2 | OXYPIPERIDINE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249098-A1 | OXYPIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF | OPRK1, GPR119, OPRD1 | L3MBTL1 2612/4885RBP4 640/4885CHRNB2 926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.