Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128811 | 0.82 | TLR9 (0.44) | L3MBTL3L3MBTL1 | |
| SCHEMBL13128814 | 0.81 | POLB (0.42) | GAAKDM4EL3MBTL1POLBMKNK1 | |
| SCHEMBL5273 | 0.80 | SIGMAR1 (0.70) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13128802 | 0.79 | L3MBTL1 (0.60) | GAAL3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13128806 | 0.79 | GPR119 (0.56) | — | |
| Hydrochloric Acid SCHEMBL1597605 | 0.78 | SIGMAR1 (0.68) | GAACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22119220 | 0.75 | KDM4E (0.59) | GAAKDM4EPOLBCHRNB2CHRNB4 | |
| SCHEMBL23094515 | 0.74 | KDM4E (0.55) | GAAKDM4EPOLBCHRNB2CHRNB4 | |
| SCHEMBL13744553 | 0.73 | ACHE (0.72) | GAAKDM4EL3MBTL3POLBRECQL | |
| SCHEMBL4703329 | 0.73 | KDM4E (0.61) | GAAKDM4EL3MBTL3L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249098-A1 | OXYPIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2010-09-30 | — | — | US | disclosed |
| US-20100249098-A1 | OXYPIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION | 2010-09-30 | — | — | US | disclosed |
| WO-2009045313-A2 | OXYPIPERIDINE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249098-A1 | OXYPIPERIDINE DERIVATIVES AND METHODS OF USE THEREOF | OPRK1, GPR119, OPRD1 | GAA 447/4885KDM4E 1134/4885L3MBTL3 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.