SCHEMBL13145151

SCHEMBL13145151

CC(Br)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.47
ADRB2 P07550 2/20 0.46
ADRB1 P08588 2/20 0.46
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 2/20 0.45
NFKB1 P19838 2/20 0.45
CYP1A2 P05177 1/20 0.45
PNMT P11086 1/20 0.45
NISCH Q9Y2I1 1/20 0.44
LMNA P02545 3/20 0.43
ALDH1A1 P00352 2/20 0.43
GLA P06280 1/20 0.43
TSHR P16473 4/20 0.43
AOC3 Q16853 1/20 0.41
HIF1A Q16665 3/20 0.41
IDO1 P14902 2/20 0.41
TDO2 P48775 2/20 0.41
IDO2 Q6ZQW0 2/20 0.41
CYP2C19 P33261 2/20 0.41
BLM P54132 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320794 1.00 P2RX7 (0.47) P2RX7ADRB2ADRB1CYP3A4CYP2D6
SCHEMBL10980261 0.81 CYP1A2 (0.63) P2RX7ADRB2ADRB1CYP3A4CYP2D6
SCHEMBL30566931 0.81 P2RX7 (0.45) P2RX7CYP3A4CYP2D6NFKB1CYP1A2
SCHEMBL1415318 0.81 P2RX7 (0.45) P2RX7CYP3A4CYP2D6NFKB1CYP1A2
SCHEMBL219293 0.80 ADRB2 (0.46) ADRB2ADRB1CYP3A4CYP2D6NFKB1
SCHEMBL1281895 0.79 P2RX7 (0.47) P2RX7ADRB2ADRB1CYP3A4CYP2D6
SCHEMBL12204154 0.79 ADRB2 (0.48) ADRB2ADRB1CYP3A4CYP2D6NFKB1
SCHEMBL9677445 0.79 TSHR (0.47) ADRB2ADRB1CYP3A4CYP2D6NFKB1
SCHEMBL84509 0.79 GABRA1 (0.50) ADRB2ADRB1CYP3A4CYP2D6NFKB1
SCHEMBL4815784 0.79 TSHR (0.47) ADRB2ADRB1CYP3A4CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000642-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS TAY THERAPEUTICS LTD (GB) 2026-01-01 US disclosed
US-20250263370-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS Tay Therapeutics Limited (GB) 2025-08-21 US disclosed
EP-4558224-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS Tay Therapeutics Limited (GB) 2025-05-28 EP disclosed
CN-115551839-B Heteroaryl-triazole compounds as pesticides 拜耳公司 2024-06-04 CN disclosed
WO-2024068656-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2024-04-04 WO disclosed
EP-4326710-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE ISOQUINOLINE DERIVATIVES Syngenta Crop Protection AG (CH) 2024-02-28 EP disclosed
WO-2024018423-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS Tay Therapeutics Limited (GB) 2024-01-25 WO disclosed
CN-117177963-A Microbiocidal quinoline/quinoxaline isoquinoline derivatives 先正达农作物保护股份公司 2023-12-05 CN disclosed
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-05-18 US disclosed
CN-115551839-A Heteroaryl-triazole compounds as pesticides 拜耳公司 2022-12-30 CN disclosed
US-7507827-B2 Stereoselective method for the production of Clopidogrel RATIOPHARM GMBH (DE) 2009-03-24 US disclosed
CN-101253164-A Indol-3-carbonyl-spiro-piperidine derivatives as v1a receptor antagonists HOFFMANN LA ROCHE (CH) 2008-08-27 CN disclosed
CN-101233139-A Alpha-(aryl-or heteroaryl-methyl)-beta-piperidinopropanoic acid compounds as ORL1-receptor antagonists PFIZER (US) 2008-07-30 CN disclosed
US-20070219166-A1 Stereoselective Method for the Production of Clopidogrel RATIOPHARM GMBH (DE) 2007-09-20 US disclosed
CN-101039907-A Isoindolone compounds and their use as metabotropic glutamate receptor potentiators ASTRAZENECA AB (SE) 2007-09-19 CN disclosed
CN-101035765-A Sulfonamide derivatives HOFFMANN LA ROCHE (CH) 2007-09-12 CN disclosed
CN-1914173-A Quinolines useful in treating cardiovascular disease WYETH CORP (US) 2007-02-14 CN disclosed
CN-1283638-C Indole-2-formamide compounds as factor Xa inhibitors AVENTIS PHARMA GMBH (DE) 2006-11-08 CN disclosed
CN-1706820-A Prepn and application of N-[2-(aryloxy)ethyl]-2-(arylthio) benzyl amine derivative UNIV TIANJIN (CN) 2005-12-14 CN disclosed
CN-1589270-A Indole-2-formamide compounds as factor Xa inhibitors AVENTIS PHARMA GMBH (DE) 2005-03-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148601-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES PRXL2A, GLRX3, CYP4F3 P2RX7 545/4885ADRB2 724/4885ADRB1 691/4885
US-20260000642-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS BET1, BRD4, PHKB P2RX7 3003/4885ADRB2 323/4885ADRB1 476/4885
US-20250263370-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS BET1, PHKB, BRD4 P2RX7 3433/4885ADRB2 3408/4885ADRB1 2811/4885
US-20070219166-A1 Stereoselective Method for the Production of Clopidogrel CYP2C19, ADH1C, TBXA2R P2RX7 383/4885ADRB2 82/4885ADRB1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.