Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766475 | 0.84 | TDP1 (0.31) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL17636222 | 0.84 | LMNA (0.44) | TSHRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3920669 | 0.81 | CA1 (0.54) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL10581532 | 0.81 | CA1 (0.44) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL11211976 | 0.80 | CA12 (0.33) | CA12CA1CA2CA9ACR | |
| Hydrochloric Acid SCHEMBL27375982 | 0.79 | CA1 (0.52) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL4099798 | 0.79 | GRIN2D (0.39) | TSHRTDP1KDM4EALDH1A1 | |
| SCHEMBL4572780 | 0.78 | CA1 (0.39) | CA12CA1CA2CA9ACR | |
| SCHEMBL10991842 | 0.78 | CA1 (0.39) | CA12CA1CA2CA9ACR | |
| SCHEMBL17870797 | 0.76 | TP53 (0.38) | CA12CA1CA2CA9ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12042550-B2 | Leave-on hair treatment compositions | L'OREAL (FR) | 2024-07-23 | — | — | US | claimed |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-18 | — | — | US | claimed |
| WO-2024073637-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-04 | — | — | WO | claimed |
| WO-2018000059-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2018-01-04 | — | — | WO | claimed |
| EP-2836188-B1 | EMULSION HAVING UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2017-11-01 | — | — | EP | claimed |
| EP-1965757-B1 | COSMETIC USE OF A HYDROXYALKYLUREA AS AN AGENT FOR TREATING DESQUAMATIVE CONDITIONS OF THE SCALP; COSMETIC TREATMENT COMPOSITIONS AND PROCESSES | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| EP-1743623-B1 | Use of urea compounds for promoting desquamation | ORÉAL L (FR) | 2016-06-29 | — | — | EP | claimed |
| EP-2988830-A2 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | L'Oréal (FR) | 2016-03-02 | — | — | EP | claimed |
| EP-2916808-A1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | L'Oréal (FR) | 2015-09-16 | — | — | EP | claimed |
| WO-2014174075-A2 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | L'OREAL (FR) | 2014-10-30 | — | — | WO | claimed |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177396-A1 | Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177394-A1 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060127343-A1 | Administration of urea compounds for combating signs of cutaneous aging | L'OREAL (FR) | 2006-06-15 | — | — | US | claimed |
| WO-2006056491-A1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A HYDROXYALKYL UREA | L'ORÉAL (FR) | 2006-06-01 | — | — | WO | claimed |
| EP-1661550-A1 | Cosmetic and/or dermatological composition comprising urea compound | L'OREAL, S.A. (FR) | 2006-05-31 | — | — | EP | claimed |
| US-20060111490-A1 | Composition comprising a urea compound | L'OREAL (FR) | 2006-05-25 | — | — | US | claimed |
| WO-2006048339-A2 | COSMETIC COMPOSITION COMRISING AN ACTIVE AGENT AND A UREA COMPOUND | L'ORÉAL (FR) | 2006-05-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | CUTA, S100A11, KRT18 | CA12 4313/4885CA1 4604/4885CA2 3309/4885 |
| US-20060177396-A1 | Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds | HCN3, KRT18, H1-0 | CA12 2541/4885CA1 3093/4885CA2 277/4885 |
| US-12042550-B2 | Leave-on hair treatment compositions | ALG3, DEGS1, DSG1 | CA12 1054/4885CA1 1819/4885CA2 3802/4885 |
| US-20060177394-A1 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | KRT18, CUTA, H1-0 | CA12 4372/4885CA1 4629/4885CA2 2857/4885 |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | H1-0, KRT18, CCNE1 | CA12 4104/4885CA1 4480/4885CA2 2816/4885 |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | ALG3, DEGS1, DSG1 | CA12 1054/4885CA1 1819/4885CA2 3802/4885 |
| US-20060127343-A1 | Administration of urea compounds for combating signs of cutaneous aging | SLC14A1, CTRL, URB2 | CA12 3065/4885CA1 2161/4885CA2 1463/4885 |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | CUTA, TYR, ADH7 | CA12 3663/4885CA1 4208/4885CA2 1631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.