SCHEMBL131807

SCHEMBL131807

COCCOCCOCCCN

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.41
CA2 P00918 3/20 0.39
CYP3A4 P08684 2/20 0.38
TSHR P16473 2/20 0.34
DDAH1 O94760 1/20 0.34
NFKB1 P19838 1/20 0.32
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
CA12 O43570 2/20 0.30
CA1 P00915 2/20 0.30
CA3 P07451 2/20 0.30
CA4 P22748 2/20 0.30
CA6 P23280 2/20 0.30
CA5A P35218 2/20 0.30
CA7 P43166 2/20 0.30
CA9 Q16790 2/20 0.30
CA14 Q9ULX7 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1280849 1.00
SCHEMBL21478685 1.00 ODC1 (0.41) ODC1CA2CYP3A4TSHRDDAH1
SCHEMBL12349346 1.00 ODC1 (0.41) ODC1CA2CYP3A4TSHRDDAH1
SCHEMBL12349367 1.00 ODC1 (0.41) ODC1CA2CYP3A4TSHRDDAH1
SCHEMBL9863417 1.00 ODC1 (0.41) ODC1CA2CYP3A4TSHRDDAH1
SCHEMBL24753245 0.97 ODC1 (0.39) ODC1CA2CYP3A4TSHRDDAH1
Hydrochloric Acid SCHEMBL4701964 0.97 ODC1 (0.39) ODC1CA2CYP3A4TSHRDDAH1
SCHEMBL5936431 0.92 CA2 (0.38) CA2CYP3A4TSHRDDAH1NFKB1
SCHEMBL19591114 0.92 ODC1 (0.39) ODC1CA2CYP3A4TSHRDDAH1
SCHEMBL18391516 0.92 CA2 (0.38) CA2CYP3A4TSHRDDAH1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381319-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (US) 2023-11-30 US disclosed
US-20230381319-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ARBUTUS BIOPHARMA CORPORATION (US) 2023-11-30 US disclosed
US-11712476-B2 Lipids and compositions for the delivery of therapeutics ARBUTUS BIOPHARMA CORPORATION (CA) 2023-08-01 US disclosed
US-20230174459-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (US) 2023-06-08 US disclosed
US-20230174459-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (US) 2023-06-08 US disclosed
US-11299635-B2 Bis-Azo colorants for use as bluing agents MILLIKEN & COMPANY (US) 2022-04-12 US disclosed
US-10876079-B2 Bis-azo colorants for use as bluing agents THE PROCTER & GAMBLE COMPANY (US) 2020-12-29 US disclosed
US-20200361854-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2020-11-19 US disclosed
US-20200225215-A1 SCREENING METHOD FOR SELECTED AMINO-LIPID-CONTAINING COMPOSITIONS ARBUTUS BIOPHARMA CORPORATION 2020-07-16 US disclosed
US-10653780-B2 Amino lipids and methods for the delivery of nucleic acids THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2020-05-19 US disclosed
US-20110117125-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2011-05-19 US disclosed
US-20110097720-A1 SCREENING METHOD FOR SELECTED AMINO LIPID-CONTAINING COMPOSITIONS ALNYLAM PHARMACEUTICALS, INC. (US) 2011-04-28 US disclosed
WO-2010151906-A2 BIS-AZO COLORANTS FOR USE AS BLUING AGENTS MILLIKEN & COMPANY (US) 2010-12-29 WO disclosed
US-20100324120-A1 LIPID FORMULATION BANK OF AMERICA, N.A. 2010-12-23 US disclosed
US-20100267806-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES ALNYLAM PHARMACEUTICALS, INC. 2010-10-21 US disclosed
US-7632682-B2 Anthraquinone colorant compositions and methods for producing the same MILLIKEN & COMPANY (US) 2009-12-15 US disclosed
US-20090023673-A1 LIPID CONTAINING FORMULATIONS BANK OF AMERICA, N.A. 2009-01-22 US disclosed
EP-1828314-A2 IMPROVED ANTHRAQUINONE COLORANT COMPOSITIONS AND METHODS FOR PRODUCING THE SAME Milliken & Company (US) 2007-09-05 EP disclosed
WO-2006062970-A2 IMPROVED ANTHRAQUINONE COLORANT COMPOSITIONS AND METHODS FOR PRODUCING THE SAME MILLIKEN & COMPANY (US) 2006-06-15 WO disclosed
US-20060117499-A1 Anthraquinone colorant compositions and methods for producing the same MILLIKEN & COMPANY 2006-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361854-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ODC1 3205/4885CA2 4453/4885CYP3A4 4794/4885
US-20100324120-A1 LIPID FORMULATION CETP, LIPA, SGMS1 ODC1 2438/4885CA2 3223/4885CYP3A4 2603/4885
US-20230381319-A1 NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS SGMS2, SGMS1, PHOSPHO1 ODC1 2393/4885CA2 4688/4885CYP3A4 3899/4885
US-20110117125-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF NUCLEIC ACIDS LDLR, SNRPE, SARNP ODC1 4422/4885CA2 3610/4885CYP3A4 4884/4885
US-20230174459-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ODC1 3205/4885CA2 4453/4885CYP3A4 4794/4885
US-10653780-B2 Amino lipids and methods for the delivery of nucleic acids NSUN3, SARNP, LDLR ODC1 3590/4885CA2 3725/4885CYP3A4 4881/4885
US-11712476-B2 Lipids and compositions for the delivery of therapeutics SGMS2, APOB, PHOSPHO1 ODC1 2538/4885CA2 3202/4885CYP3A4 3740/4885
US-20090023673-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 ODC1 3205/4885CA2 4453/4885CYP3A4 4794/4885
US-20100267806-A1 LIPID FORMULATED COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF Eg5 AND VEGF GENES KIF5A, KIF5C, KIF11 ODC1 4171/4885CA2 3977/4885CYP3A4 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.