Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12650870 | 0.83 | MAOA (0.39) | MAOAMAOBNOTUMOPRM1OPRL1 | |
| SCHEMBL13416638 | 0.83 | MAOA (0.39) | MAOAMAOBNOTUMOPRM1OPRL1 | |
| SCHEMBL19356295 | 0.82 | CARM1 (0.36) | MAOAMAOBCARM1OPRM1OPRL1 | |
| SCHEMBL23349351 | 0.82 | CARM1 (0.36) | MAOAMAOBCARM1OPRM1OPRL1 | |
| SCHEMBL13693198 | 0.79 | DPP8 (0.39) | MAOAMAOBOPRM1OPRL1ACE | |
| SCHEMBL19356297 | 0.76 | ALDH1A1 (0.40) | NOTUMCARM1OPRM1OPRL1ACE | |
| SCHEMBL19356296 | 0.76 | ALDH1A1 (0.40) | NOTUMCARM1OPRM1OPRL1ACE | |
| SCHEMBL4692862 | 0.73 | NOTUM (0.41) | NOTUMACEPOLBAPOBEC3AAPOBEC3G | |
| SCHEMBL8324725 | 0.72 | MAOA (0.43) | MAOAMAOBNOTUMOPRM1OPRL1 | |
| SCHEMBL15222058 | 0.72 | MAOA (0.43) | MAOAMAOBNOTUMOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234334-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2010-09-16 | — | — | US | disclosed |
| US-20100093685-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. | 2010-04-15 | — | — | US | disclosed |
| US-20100041633-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2010-02-18 | — | — | US | disclosed |
| WO-2008095806-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008095809-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008095808-A1 | NITRIC OXIDE RELEASING STEROIDS | NICOX S.A. (FR) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041633-A1 | NITRIC OXIDE RELEASING STEROIDS | CYP11B1, CYP11B2, NOS1 | MAOA 653/4885MAOB 552/4885NOTUM 750/4885 |
| US-20100093685-A1 | NITRIC OXIDE RELEASING STEROIDS | NR3C1, CYP11B1, NOS1 | MAOA 676/4885MAOB 560/4885NOTUM 1977/4885 |
| US-20100234334-A1 | NITRIC OXIDE RELEASING STEROIDS | NOS1, NR3C1, NOS2 | MAOA 489/4885MAOB 356/4885NOTUM 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.