Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274787 | 0.76 | IDH1 (0.46) | MEN1GLACYP3A4KMT2AMMP3 | |
| SCHEMBL8270273 | 0.74 | ALOX5 (0.45) | MEN1GLACYP3A4KMT2ACA1 | |
| SCHEMBL10032701 | 0.69 | ALOX5 (0.45) | CYP3A4CA1ALOX5CA2BCL2 | |
| SCHEMBL19766982 | 0.67 | GABRA1 (0.33) | CYP3A4CA1CA2PTGS1LMNA | |
| SCHEMBL12848863 | 0.67 | MEN1 (0.38) | MEN1GLACYP3A4KMT2ACA1 | |
| SCHEMBL19349230 | 0.67 | MMP3 (0.51) | MEN1GLACYP3A4KMT2ACA1 | |
| SCHEMBL6991694 | 0.63 | IDH1 (0.45) | MEN1GLACYP3A4KMT2AMMP3 | |
| SCHEMBL8833077 | 0.63 | ABCB1 (0.50) | MEN1CYP3A4KMT2AALOX5PTGS1 | |
| SCHEMBL21968128 | 0.63 | ALDH1A1 (0.32) | MEN1GLACYP3A4KMT2ACA2 | |
| SCHEMBL8833175 | 0.62 | HSD17B10 (0.50) | MEN1GLACYP3A4KMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786316-B2 | Metalloprotein inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-08-31 | — | — | US | disclosed |
| US-20090286987-A1 | METALLOPROTEIN INHIBITORS | REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO UCSD TECHNOLOGY TRANSFER OFFICE (US) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286987-A1 | METALLOPROTEIN INHIBITORS | SOD1, ZFX, SOD3 | MEN1 1721/4885GLA 117/4885CYP3A4 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.