Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11807767 | 0.79 | GABRA1 (0.46) | ALOX15ALOX12GABRA1GABRB2GRIN2D | |
| SCHEMBL21884099 | 0.77 | GABRA1 (0.43) | ALOX15ALOX12GABRA1GABRB2GRIN2D | |
| SCHEMBL10799329 | 0.74 | GABRA1 (0.42) | ALOX15ALOX12GABRA1GABRB2GRIN2D | |
| SCHEMBL861792 | 0.72 | NOS3 (0.37) | ALOX15ALOX12GABRA1GABRB2TAAR1 | |
| SCHEMBL2747477 | 0.72 | GABRA1 (0.35) | ALOX15ALOX12GABRA1GABRB2 | |
| SCHEMBL28393776 | 0.69 | ALOX15 (0.50) | ALOX15ALOX12ALDH1A1 | |
| SCHEMBL6650753 | 0.68 | PYCR1 (0.43) | ALOX15ALOX12GABRA1GABRB2ALDH1A1 | |
| SCHEMBL19186444 | 0.68 | GABRA1 (0.52) | ALOX15ALOX12GABRA1GABRB2ALDH1A1 | |
| SCHEMBL30301261 | 0.68 | ALOX15 (0.36) | ALOX15ALOX12GABRA1GABRB2TAAR1 | |
| SCHEMBL169822 | 0.68 | ALOX15 (0.36) | ALOX15ALOX12GABRA1GABRB2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767657-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2010-08-03 | — | — | US | disclosed |
| US-20070155699-A1 | Boron-containing small molecules | ANACOR PHARMACEUTICALS (US) | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155699-A1 | Boron-containing small molecules | ETF1, POLR1C, DPM1 | ALOX15 2614/4885ALOX12 2348/4885GABRA1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.