SCHEMBL861792

SCHEMBL861792

CC(C)Cc1cc(N)c(Br)cc1CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
NOS2 P35228 1/20 0.37
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
HTR2A P28223 3/20 0.34
TAAR1 Q96RJ0 2/20 0.34
POLB P06746 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
NR4A1 P22736 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13248013 0.72 ALOX15 (0.44) ALOX15ALOX12GABRA1GABRB2HTR2A
SCHEMBL11851884 0.71 ALDH1A1 (0.46) NOS3NOS1NOS2ALOX15GABRA1
SCHEMBL2416692 0.71 GABRA1 (0.44) GABRA1GABRB2HTR2AALDH1A1BLM
SCHEMBL10409265 0.71 KDM4E (0.37) GABRA1GABRB2HTR2AMEN1ALDH1A1
SCHEMBL12320858 0.71 GABRA1 (0.36) ALOX15GABRA1GABRB2HTR2AMEN1
SCHEMBL24807660 0.70 CTSB (0.42) GABRA1GABRB2HTR2AMAPT
SCHEMBL6572888 0.70 ALDH1A1 (0.61) NOS3NOS1NOS2ALOX15GABRA1
SCHEMBL841100 0.70 ALDH1A1 (0.33) ALOX15POLBL3MBTL1MEN1APAF1
SCHEMBL18853826 0.68 NOS2 (0.48) NOS3NOS1NOS2GABRA1GABRB2
SCHEMBL9791514 0.68 GABRA1 (0.33) NOS3NOS1NOS2GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C NOS3 3229/4885NOS1 2926/4885NOS2 3207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.