Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000033 | 0.84 | LMNA (0.53) | LMNAMAPTALDH1A1KDM4EPKN1 | |
| SCHEMBL538459 | 0.80 | NPC1 (0.52) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL5219548 | 0.77 | DGAT1 (0.41) | MAPTALDH1A1CYP2D6MEN1MAPK1 | |
| SCHEMBL19569164 | 0.77 | NISCH (0.42) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL15452781 | 0.76 | ALDH1A1 (0.50) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL912607 | 0.74 | MAPT (0.42) | LMNAMAPTALDH1A1KDM4EPKN1 | |
| SCHEMBL420012 | 0.74 | MGAM (0.43) | LMNAMAPTALDH1A1KDM4EPKN1 | |
| SCHEMBL12766232 | 0.74 | PRKCZ (0.49) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16896271 | 0.72 | LMNA (0.40) | LMNAMAPTALDH1A1KDM4EPKN1 | |
| SCHEMBL10022693 | 0.72 | RAB9A (0.46) | MAPTALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104087145-B | A kind of fire-retardant preparation method with germ resistance aqueous polyurethane coating | DUAN BAORONG (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-104087145-A | Preparation method of flame-retardant and antibacterial water-based polyurethane coating | DUAN BAORONG | 2014-10-08 | — | — | CN | claimed |
| US-20250367209-A1 | IDENTIFICATION OF NOVEL BENZOTHIAZONES AS TAU-SH3 INTERACTION INHIBITORS FOR THE TREATMENT OF ALZHEIMER’S DISEASE | SOUTHERN RES INST (US) | 2025-12-04 | — | — | US | disclosed |
| US-12404265-B2 | Substituted pyridine derivatives as SARM1 inhibitors | NURA BIO, INC. (US) | 2025-09-02 | — | — | US | disclosed |
| US-11970481-B1 | Substituted pyridine derivatives as SARM1 inhibitors | NURA BIO, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| US-20240116901-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. | 2024-04-11 | — | — | US | disclosed |
| WO-2023250002-A1 | IDENTIFICATION OF NOVEL BENZOTHIAZONES AS TAU-SH3 INTERACTION INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | SOUTHERN RESEARCH INSTITUTE (US) | 2023-12-28 | — | — | WO | disclosed |
| US-20230339913-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. | 2023-10-26 | — | — | US | disclosed |
| US-20230339913-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | NURA BIO, INC. | 2023-10-26 | — | — | US | disclosed |
| EP-4192828-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | Nura Bio, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| US-20230008433-A1 | Inhibitors of SARM1 | DISARM THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |
| CN-104087145-B | A kind of fire-retardant preparation method with germ resistance aqueous polyurethane coating | DUAN BAORONG (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-104087145-A | Preparation method of flame-retardant and antibacterial water-based polyurethane coating | DUAN BAORONG | 2014-10-08 | — | — | CN | disclosed |
| WO-2010093849-A2 | PHENYLALANINE AMIDE DERIVATIVES USEFUL FOR TREATING INSULIN-RELATED DISEASES AND CONDITIONS | AMGEN INC. (US) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404265-B2 | Substituted pyridine derivatives as SARM1 inhibitors | SARM1, SARNP, ADRM1 | LMNA 2012/4885MAPT 45/4885ALDH1A1 3991/4885 |
| US-11970481-B1 | Substituted pyridine derivatives as SARM1 inhibitors | SARM1, SARNP, ADRM1 | LMNA 2012/4885MAPT 45/4885ALDH1A1 3991/4885 |
| US-20230339913-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | SARM1, SARNP, ADRM1 | LMNA 2012/4885MAPT 45/4885ALDH1A1 3991/4885 |
| US-20230008433-A1 | Inhibitors of SARM1 | SARM1, SMN1; SMN2, SARNP | LMNA 1340/4885MAPT 89/4885ALDH1A1 4157/4885 |
| US-20240116901-A1 | SUBSTITUTED PYRIDINE DERIVATIVES AS SARM1 INHIBITORS | SARM1, SARNP, ADRM1 | LMNA 2012/4885MAPT 45/4885ALDH1A1 3991/4885 |
| US-20250367209-A1 | IDENTIFICATION OF NOVEL BENZOTHIAZONES AS TAU-SH3 INTERACTION INHIBITORS FOR THE TREATMENT OF ALZHEIMER’S DISEASE | MAPT, SORBS1, TARDBP | LMNA 4187/4885MAPT 1/4885ALDH1A1 2271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.