Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.65 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265821 | 0.87 | RORC (0.74) | RORCKCNMA1ALDH1A1PKMCRHBP | |
| SCHEMBL13265724 | 0.87 | RORC (0.65) | RORCKCNMA1ALDH1A1PKMCRHBP | |
| SCHEMBL13265792 | 0.85 | MAPT (0.60) | KCNMA1ALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL13265794 | 0.84 | MAPT (0.64) | RORCALDH1A1PKMKMT2AMEN1 | |
| SCHEMBL13265957 | 0.83 | RAB9A (0.73) | RORCKCNMA1ALDH1A1PKMCRHBP | |
| SCHEMBL6815623 | 0.81 | KCNMA1 (0.77) | RORCKCNMA1ALDH1A1PKMCRHBP | |
| SCHEMBL29886399 | 0.81 | KCNMA1 (0.77) | RORCKCNMA1ALDH1A1PKMCRHBP | |
| SCHEMBL26758015 | 0.81 | RORC (0.78) | RORCKCNMA1ALDH1A1PKMCRHBP | |
| SCHEMBL22114132 | 0.80 | HSPB1 (0.63) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL13265800 | 0.80 | MEN1 (0.64) | RORCKCNMA1ALDH1A1PKMCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754773-B2 | Composition and synthesis of new reagents for inhibition of HIV replication | UNIVERSITY OF MASSACHUSETTS (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099919-A1 | Composition and synthesis of new reagents for inhibition of HIV replication | REV1, MAVS, ISG15 | RORC 3548/4885KCNMA1 4468/4885ALDH1A1 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.