Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 2/20 | 0.50 |
| ▸ | MMP7 | P09237 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13244664 | 0.91 | ADAMTS4 (0.55) | ADAMTS4MMP1MMP7MMP9MMP13 | |
| SCHEMBL13267165 | 0.83 | ADAMTS4 (0.54) | ADAMTS4MMP1MMP2MMP3MMP9 | |
| SCHEMBL14400854 | 0.81 | KMT2A (0.51) | — | |
| SCHEMBL9925870 | 0.81 | KMT2A (0.51) | — | |
| SCHEMBL1109224 | 0.81 | KMT2A (0.51) | — | |
| SCHEMBL13266951 | 0.81 | HRH3 (0.46) | ADAMTS4 | |
| SCHEMBL13984815 | 0.80 | MMP2 (0.71) | ADAMTS4MMP1MMP2MMP3MMP7 | |
| SCHEMBL13266866 | 0.80 | MMP2 (0.71) | ADAMTS4MMP1MMP2MMP3MMP7 | |
| SCHEMBL13267412 | 0.78 | HRH3 (0.48) | — | |
| SCHEMBL13244849 | 0.78 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | ADAMTS4 3184/4885MMP1 926/4885MMP2 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.