Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 1.00 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 3/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341627 | 0.84 | MTNR1A (0.72) | MTNR1AALDH1A1POLB | |
| SCHEMBL7201020 | 0.81 | MTNR1A (0.74) | MTNR1AMAPTALDH1A1ALOX5POLB | |
| SCHEMBL5225019 | 0.80 | MTNR1A (0.67) | MTNR1ANQO2MTNR1B | |
| SCHEMBL132847 | 0.80 | MTNR1A (0.66) | MTNR1ANQO2MTNR1B | |
| SCHEMBL11219443 | 0.78 | MTNR1A (0.64) | MTNR1AFFAR1MAPTGAAALDH1A1 | |
| SCHEMBL6982719 | 0.78 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAALDH1A1 | |
| SCHEMBL29444764 | 0.78 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAALDH1A1 | |
| SCHEMBL1870686 | 0.78 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAALDH1A1 | |
| SCHEMBL5228871 | 0.78 | MTNR1A (1.00) | MTNR1ANQO2MTNR1BPOLB | |
| SCHEMBL15870218 | 0.76 | MTNR1A (0.61) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230052740-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-02-16 | — | — | US | disclosed |
| WO-2021041702-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-04 | — | — | WO | disclosed |
| US-6602903-B2 | Substituted O- and/or S heterocyclic compounds; powerful ligands for melatoninergic receptors. | LES LABORATORIES SERVIER (FR) | 2003-08-05 | — | — | US | disclosed |
| US-20020052400-A1 | Substituted heterocyclic compounds | ADIR ET COMPAGNIE | 2002-05-02 | — | — | US | disclosed |
| US-6313160-B1 | FOR THERAPY AND PROPHYLAXIS OF MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-0998471-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 2000-05-10 | — | — | EP | disclosed |
| WO-1998052935-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR PREPARING AND COMPOSITIONS CONTAINING SAME | ADIR ET COMPAGNIE (FR) | 1998-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230052740-A1 | MODULATORS OF CIRCADIAN RHYTHMS AND USES THEREOF | MTNR1A, PER2, MTNR1B | MTNR1A 1/4885FFAR1 1363/4885MAPT 1632/4885 |
| US-20020052400-A1 | Substituted heterocyclic compounds | MTNR1A, MTNR1B, CBR1 | MTNR1A 1/4885FFAR1 612/4885MAPT 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.